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Browsing publications by Marian Case.

Newcastle AuthorsTitleYearFull text
Marian Case
Dr Dino Masic
Dr David Jamieson
Dr Frederik van Delft
Dr Andrew Filby
et al.
Label-Free Leukemia Monitoring by Computer Vision2020
Liz Matheson
Huw Thomas
Marian Case
Dr Helen Blair
Rosanna Jackson
et al.
Glucocorticoids and selumetinib are highly synergistic in RAS pathway mutated childhood acute lymphoblastic leukemia through upregulation of BIM2019
Dr Paul Sinclair
Dr Sarra Ryan
Dr Matthew Bashton
Shaun Hollern
Rebecca Hanna
et al.
SH2B3 inactivation through CN-LOH-12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain2019
Dr Britta Vormoor
Professor Gareth Veal
Melanie Griffin
Professor Julie Irving
Lynne Minto
et al.
A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia2017
Judith Weiland
Dr Deepali Pal
Marian Case
Professor Julie Irving
Dr Frida Ponthan
et al.
BCP-ALL blasts are not dependent on CD19 expression for leukaemic maintenance2016
Dr Lindsay Nicholson
Elizabeth Matheson
Lynne Minto
Christopher Keilty
Maryna Sanichar
et al.
Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition2015
Professor Julie Irving
Elizabeth Matheson
Helen Blair
Marian Case
Isabella Swidenbank
et al.
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition. Blood. 2014;124(23):3420-34302015
Professor Julie Irving
Elizabeth Matheson
Dr Helen Blair
Marian Case
Isabella Swidenbank
et al.
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition2014
Dr Lindsay Nicholson
Elizabeth Matheson
Lynne Minto
Marian Case
Maryna Sanichar
et al.
Casitas B lymphoma mutations in childhood acute lymphoblastic leukemia2012
Sarina Sulong
Professor Anthony Moorman
Professor Julie Irving
Marian Case
Professor Simon Bailey
et al.
A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups2009
Professor Julie Irving
Marian Case
Lynne Minto
Sally Lawson
Establishment and validation of a standard protocol for the detection of minimal residual disease in B lineage childhood acute lymphoblastic leukemia by flow cytometry in a multi-center setting2009
Kate Wilson
Marian Case
Lynne Minto
Professor Simon Bailey
Dr Nicholas Bown
et al.
Flow minimal residue disease monitoring of candidate leukemic stem cells defined by the immunophenotype, CD34+CD38lowCD19+ in B-lineage childhoood acute lymphoblastic leukemia2009
Kerrie Wilson
Dr Klaus Rehe
Dr Simon Bomken
Marian Case
Professor Julie Irving
et al.
In Childhood ALL, Both Blasts with a CD20(-/Low) and a CD20(High) Immunophenotype, Have the Ability to Transfer the Leukemia Onto Immune-Deficient NOD/Scid Y-/- Mice2008
Professor Anthony Moorman
Sarina Sulong
Professor Julie Irving
Marian Case
Lynne Minto
et al.
Inactivation of CDKN2A in childhood acute lymphoblastic leukaemia (ALL) occurs principally by deletion and is strongly correlated with cytogenetic subgroups2008
Marian Case
Elizabeth Matheson
Lynne Minto
Dr Nicholas Bown
Professor Simon Bailey
et al.
Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia2008
Marian Case
Elizabeth Matheson
Lynne Minto
Professor Christine Harrison FRCPath FMedSci
Dr Nicholas Bown
et al.
Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting2008
Kerrie Wilson
Marian Case
Lynne Minto
Professor Simon Bailey
Professor Hermann Josef Vormoor
et al.
The CD34+ CD38Low CD19+ Candidate Leukemic Stem Cell Phenotype Revisited: Useful for Flow MRD Monitoring?2008
Marian Case
Dr Tina Davies
Professor Anthony Moorman
Dr Andrew Hall
Professor Julie Irving
et al.
The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR12008
Dr Linda Hogarth
Dr Chris Redfern
Dr Andrew Hall
Dr Holly Anderson
Marian Case
et al.
The effect of thiopurine drugs on DNA methylation in relation to TPMT expression2008
Elizabeth Matheson
Dr Linda Hogarth
Marian Case
Professor Julie Irving
Dr Andrew Hall
et al.
DHFR and MSH3 co-amplification in childhood acute lymphoblastic leukaemia, in vitro and in vivo2007
Professor Anthony Moorman
Marian Case
Professor Julie Irving
Dr Andrew Hall
Professor Christine Harrison FRCPath FMedSci
et al.
Genomic profiling reveals multiple genetic targets in ETV6-RUNX1 positive acute lymphoblastic leukaemia (ALL)2007
Dr Jane Carr-Wilkinson
Dr Nicholas Bown
Marian Case
Dr Andrew Hall
Professor John Lunec
et al.
High-resolution analysis of allelic imbalance in neuroblastoma cell lines by single nucleotide polymorphism arrays2007
Adillah Binti Yusof
Professor Julie Irving
Marian Case
Lynne Minto
Professor Christine Harrison FRCPath FMedSci
et al.
Red blood cell alloimmunization is affected by depletion of donor white cell subsets2007
Dr Andrew Hall
Sarina Sulong
Professor Christine Harrison FRCPath FMedSci
Lynne Minto
Dr Nicholas Bown
et al.
Assessment of aneuploidy in childhood acute lymphoblastic leukaemia using high density oligonucleotide arrays.2006
Sarina Sulong
Professor Julie Irving
Marian Case
Lynne Minto
Dr Nicholas Bown
et al.
Comprehensive analysis of p16(INK4a) in childhood acute lymphoblastic leukemia reveals homozygous deletion, haploinsufficiency and acquired isodisomy at the 9p locus with intact p16(INK4a).2006
Marian Case
Dr Andrew Hall
Dr Linda Hogarth
Amanda Jones
Design, synthesis and initial in vitro evaluation of novel prodrugs for the treatment of cystinosis2006
Mark Leslie
Marian Case
Dr Andrew Hall
Dr Sally Coulthard
Expression levels of asparagine synthetase in blasts from children and adults with acute lymphoblastic leukaemia2006
Professor Julie Irving
Lynne Minto
Elizabeth Matheson
Marian Case
Professor Simon Bailey
et al.
Mutation in genes impacting on the RAS-RAF-MEK-ERK pathway are found at high incidence in childhood acute lymphoblastic leukemia at both diagnosis and at relapse.2006
Professor Julie Irving
Clare Bloodworth
Dr Nicholas Bown
Marian Case
Dr Linda Hogarth
et al.
Loss of heterozygosity in childhood acute lymphoblastic leukemia detected by genome-wide microarray single nucleotide polymorphism analysis2005
Sarina Sulong
Marian Case
Lynne Minto
Dr Bridget Wilkins
Dr Andrew Hall
et al.
The V617F mutation in Jak2 is not found in childhood acute lymphoblastic leukaemia2005
Mark Leslie
Marian Case
Dr Andrew Hall
Dr Sally Coulthard
Potential use of asparagine synthetase levels in the individualisation of L-asparaginase therapy2003
Mark Leslie
Marian Case
Dr Andrew Hall
Dr Sally Coulthard
Measurement of aspargine synthetase mRNA levels by real-time PCR2001
Marian Case
Dr Andrew Hall
Glutathione homeostasis in buthionine sulfoximine sensitive and resistant neuroblastoma cell lines2000
Marian Case
Professor Alastair Burt
Joan Hughes
Dr Jeremy Palmer
Professor Margaret Bassendine
et al.
Erratum to 'Enhanced ultrasensitive detection of structurally diverse antigens using a single immuno-PCR assay protocol' (Journal of Immunological Methods (1999) 223 (93-106))1999
Dr Glenn Major
Sarah Jane Ross
Marian Case
Evidence for autoproteolysis of substrate-inactivated O-6-methylguanine-DNA methyltransferase following DNA repair1999