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Browsing publications by Dr Ed Schwalbe.

Newcastle AuthorsTitleYearFull text
Dr Florence Burté
Magretta Adiamah
Dr Fatma Scerif
Dr Debbie Hicks
Dr Ed Schwalbe
et al.
Metabolite profiles of medulloblastoma for rapid and non-invasive detection of molecular disease groups2024
Professor Steven Clifford
Dr Ed Schwalbe
Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome2023
James Hacking
Dr Dean Thompson
Dr Ed Schwalbe
Professor Steven Clifford
Dr Daniel Williamson
et al.
Deriving a continuum score for group 3 and 4 medulloblastoma tumor samples analyzed via RNA-sequencing or DNA methylation microarray2023
Dr Simon Bomken
Dr Amir Enshaei
Dr Ed Schwalbe
Dr Aneta Mikulasova
Dr Masood Zaka
et al.
Molecular characterisation and clinical outcome of B-cell precursor acute lymphoblastic leukaemia with IG-MYC rearrangement2023
Dr Daniel Williamson
Dr Ed Schwalbe
Professor Simon Bailey
Professor Steven Clifford
Timing is everything: A connection between medulloblastoma prognosis and foetal cerebellar development2023
Dr Jack Goddard
Jemma Castle
Emily Southworth
Anya Fletcher
Dr Stephen Crosier
et al.
MEDB-71. Molecular characterisation of Group 4 medulloblastoma improves risk-stratification and its biological understanding2022
Dr Daniel Williamson
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Janet Lindsey
Dr Stephen Crosier
et al.
Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development2022
Dr Marina Danilenko
Dr Claire Keeling
Dr Stephen Crosier
Dr Martina Finetti
Dr Daniel Williamson
et al.
Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development2022
Ruxandra Neatu
Dr Dean Thompson
Dr Ed Schwalbe
Dr Stephany Veuger
The Idiopathic Pulmonary Fibrosis-Associated Single Nucleotide Polymorphism RS35705950 Is Transcribed in a MUC5B Promoter Associated Long Non-Coding RNA (AC061979.1)2022
Dr Stephen Crosier
Dr Debbie Hicks
Dr Ed Schwalbe
Dr Daniel Williamson
Amanda Smith
et al.
Advanced molecular pathology for rare tumours: A national feasibility study and model for centralised medulloblastoma diagnostics2021
Dr Ed Schwalbe
- Lalchungnunga
Dr Timothy Barrow
Dr Gordon Strathdee
Integration of genome-level data to allow identification of subtype-specific vulnerability genes as novel therapeutic targets2021
Dr Marina Danilenko
Professor Steven Clifford
Dr Ed Schwalbe
Inter and intra-tumoral heterogeneity as a platform for personalized therapies in medulloblastoma2021
Dr Debbie Hicks
Dr Reza Rafiee
Dr Ed Schwalbe
Dr Christopher Howell
Dr Janet Lindsey
et al.
The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second-generation subtypes2021
Dr Ed Schwalbe
Dr Peter Carey
Professor Stephen O'Brien
Professor Anthony Moorman
Emilio Barretta
et al.
Challenges of starting treatment protocols for acute lymphoblastic leukaemia in a low-income setting — the Blantyre experience2020
Dr Ed Schwalbe
Dr Debbie Hicks
Professor Steven Clifford
Effects of the growth pattern of medulloblastoma on short-term neurological impairments after surgery: Results from the prospective multicenter HIT-SIOP PNET 4 study2020
Dr Yura Grabovska
Dr Stephen Crosier
Dr Martina Finetti
Dr Ed Schwalbe
Dr Rebecca Hill
et al.
Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity2020
Dr Rebecca Hill
Dr Stacey Richardson
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Janet Lindsey
et al.
Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study2020
Dr Kirsty Hodgson
Dr Ed Schwalbe
Dr Jonathan Coxhead
Naomi Sinclair
Dr Simon Cockell
et al.
Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome2019
Professor Steven Clifford
Dr Ed Schwalbe
Dr Debbie Hicks
Imaging Characteristics of Wingless Pathway Subgroup Medulloblastomas: Results from the German HIT/SIOP-Trial Cohort2019
Dr Ed Schwalbe
Dr Daniel Williamson
Dr Janet Lindsey
Dr Rebecca Hill
Dr Debbie Hicks
et al.
Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes2019
Dr Paul Sinclair
Dr Sarra Ryan
Dr Matthew Bashton
Shaun Hollern
Rebecca Hanna
et al.
SH2B3 inactivation through CN-LOH-12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain2019
Dr Ed Schwalbe
Dr Debbie Hicks
Professor Steven Clifford
Prognostic impact of whole chromosomal 1 aberration signatures in standard-risk non-WNT/non-SHH medulloblastoma: a retrospective molecular analysis of the HIT-SIOP-PNET4 clinical trial2018
Dr Darren Smith
Professor Nicholas Embleton
Professor Janet Berrington
Dr Ed Schwalbe
Dr Clare Lanyon
et al.
Response: Commentary: Reducing Viability Bias in Analysis of Gut Microbiota in Preterm Infants at Risk of NEC and Sepsis2018
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Matthew Bashton
Dr Amir Enshaei
et al.
Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures2017
Dr Ed Schwalbe
Dr Janet Lindsey
Dr Sirintra Nakjang
Dr Stephen Crosier
Amanda Smith
et al.
Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study2017
Dr Darren Smith
Professor Nicholas Embleton
Professor Janet Berrington
Dr Ed Schwalbe
Dr Clare Lanyon
et al.
Reducing Viability Bias in Analysis of Gut Microbiota in Preterm Infants at Risk of NEC and Sepsis2017
Dr Ed Schwalbe
Dr Kevin Windebank
Professor Stephen O'Brien
Dr Peter Carey
Professor Simon Bailey
et al.
The use of anthracyclines in the treatment of endemic Burkitt lymphoma2017
Dr Stephen Crosier
Dr Debbie Hicks
Dr Ed Schwalbe
Dr Daniel Williamson
Sarah Nicholson
et al.
Centralised Molecular Pathology for Rare Tumours: A National Feasibility Study of Real-Time Medulloblastoma Diagnostics2016
Dr Daniel Williamson
Dr Janet Lindsey
Dr Debbie Hicks
Dr Stephen Crosier
Amanda Smith
et al.
The Transcriptional Landscape of Medulloblastoma: Group 3 and Group 4 Tumours Comprise a Single Clinically Significant Expression Continuum2016
Professor Steven Clifford
Dr Ed Schwalbe
Dr Debbie Hicks
Kieran O'Toole
Sarah Nicholson
et al.
Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial2015
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Karen Barker
Dr Daniel Williamson
et al.
Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease2015
Dr Ed Schwalbe
Professor Steven Clifford
DNA Methylation Analysis of Paediatric Low-Grade Astrocytomas Identifies a Tumour-Specific Signature at a Set of Enhancers2015
Dr Ed Schwalbe
Dr Kevin Windebank
Dr Peter Carey
Professor Simon Bailey
The Role of Anthracyclines in the Treatment of Endemic Burkitt Lymphoma2015
Dr Ed Schwalbe
Dr Lucy Chilton
Glycerol and acetaminophen as adjuvant therapy did not affect the outcome of bacterial meningitis in Malawian children.2014
Fadhel Alsaid Naji
Dr Vikki Rand
Professor Anthony Moorman
Dr Ed Schwalbe
Dr Amir Enshaei
et al.
Investigation of methylation based biomarkers for prediction of relapse in good prognostic cytogenetic subgroups of childhood acute lymphoblastic leukaemia2014
Dr Ed Schwalbe
Dr Daniel Williamson
Dr Janet Lindsey
Dolores Hamilton
Sarra Ryan
et al.
DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies2013
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Professor Simon Bailey
Professor Steven Clifford
et al.
Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma2013
Dr Sarra Ryan
Dr Ed Schwalbe
Mike Cole
Yuan Lu
Dr Meryl Lusher
et al.
MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma2012
Dr Ed Schwalbe
Professor Steven Clifford
Genome-Wide Analysis of Alternative Splicing in Medulloblastoma Identifies Splicing Patterns Characteristic of Normal Cerebellar Development2011