Publications by Dr Ed Schwalbe - ePrints

Browsing publications by Dr Ed Schwalbe.

Newcastle Authors	Title	Year
Dr Florence Burté Magretta Adiamah Dr Fatma Scerif Dr Debbie Hicks Dr Ed Schwalbe et al.	Metabolite profiles of medulloblastoma for rapid and non-invasive detection of molecular disease groups	2024
Professor Steven Clifford Dr Ed Schwalbe	Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome	2023
James Hacking Dr Dean Thompson Dr Ed Schwalbe Professor Steven Clifford Dr Daniel Williamson et al.	Deriving a continuum score for group 3 and 4 medulloblastoma tumor samples analyzed via RNA-sequencing or DNA methylation microarray	2023
Dr Simon Bomken Dr Amir Enshaei Dr Ed Schwalbe Dr Aneta Mikulasova Dr Masood Zaka et al.	Molecular characterisation and clinical outcome of B-cell precursor acute lymphoblastic leukaemia with IG-MYC rearrangement	2023
Dr Daniel Williamson Dr Ed Schwalbe Professor Simon Bailey Professor Steven Clifford	Timing is everything: A connection between medulloblastoma prognosis and foetal cerebellar development	2023
Dr Stacey Richardson Dr Rebecca Hill Dr Christopher Kui Dr Janet Lindsey Dr Yura Grabovska et al.	Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse	2022
Dr Jack Goddard Jemma Castle Emily Southworth Anya Fletcher Dr Stephen Crosier et al.	MEDB-71. Molecular characterisation of Group 4 medulloblastoma improves risk-stratification and its biological understanding	2022
Dr Daniel Williamson Dr Ed Schwalbe Dr Debbie Hicks Dr Janet Lindsey Dr Stephen Crosier et al.	Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development	2022
Dr Marina Danilenko Dr Claire Keeling Dr Stephen Crosier Dr Martina Finetti Dr Daniel Williamson et al.	Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development	2022
Ruxandra Neatu Dr Dean Thompson Dr Ed Schwalbe Dr Stephany Veuger	The Idiopathic Pulmonary Fibrosis-Associated Single Nucleotide Polymorphism RS35705950 Is Transcribed in a MUC5B Promoter Associated Long Non-Coding RNA (AC061979.1)	2022
Dr Stephen Crosier Dr Debbie Hicks Dr Ed Schwalbe Dr Daniel Williamson Amanda Smith et al.	Advanced molecular pathology for rare tumours: A national feasibility study and model for centralised medulloblastoma diagnostics	2021
Dr Ed Schwalbe - Lalchungnunga Dr Timothy Barrow Dr Gordon Strathdee	Integration of genome-level data to allow identification of subtype-specific vulnerability genes as novel therapeutic targets	2021
Dr Marina Danilenko Professor Steven Clifford Dr Ed Schwalbe	Inter and intra-tumoral heterogeneity as a platform for personalized therapies in medulloblastoma	2021
Dr Debbie Hicks Dr Reza Rafiee Dr Ed Schwalbe Dr Christopher Howell Dr Janet Lindsey et al.	The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second-generation subtypes	2021
Dr Ed Schwalbe Dr Peter Carey Professor Stephen O'Brien Professor Anthony Moorman Emilio Barretta et al.	Challenges of starting treatment protocols for acute lymphoblastic leukaemia in a low-income setting — the Blantyre experience	2020
Dr Ed Schwalbe Dr Debbie Hicks Professor Steven Clifford	Effects of the growth pattern of medulloblastoma on short-term neurological impairments after surgery: Results from the prospective multicenter HIT-SIOP PNET 4 study	2020
Dr Yura Grabovska Dr Stephen Crosier Dr Martina Finetti Dr Ed Schwalbe Dr Rebecca Hill et al.	Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity	2020
Dr Rebecca Hill Dr Stacey Richardson Dr Ed Schwalbe Dr Debbie Hicks Dr Janet Lindsey et al.	Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study	2020
Dr Kirsty Hodgson Dr Ed Schwalbe Dr Jonathan Coxhead Naomi Sinclair Dr Simon Cockell et al.	Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome	2019
Professor Steven Clifford Dr Ed Schwalbe Dr Debbie Hicks	Imaging Characteristics of Wingless Pathway Subgroup Medulloblastomas: Results from the German HIT/SIOP-Trial Cohort	2019
Dr Ed Schwalbe Dr Daniel Williamson Dr Janet Lindsey Dr Rebecca Hill Dr Debbie Hicks et al.	Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes	2019
Dr Paul Sinclair Dr Sarra Ryan Dr Matthew Bashton Shaun Hollern Rebecca Hanna et al.	SH2B3 inactivation through CN-LOH-12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain	2019
Dr Ed Schwalbe Dr Debbie Hicks Professor Steven Clifford	Prognostic impact of whole chromosomal 1 aberration signatures in standard-risk non-WNT/non-SHH medulloblastoma: a retrospective molecular analysis of the HIT-SIOP-PNET4 clinical trial	2018
Dr Darren Smith Professor Nicholas Embleton Professor Janet Berrington Dr Ed Schwalbe Dr Clare Lanyon et al.	Response: Commentary: Reducing Viability Bias in Analysis of Gut Microbiota in Preterm Infants at Risk of NEC and Sepsis	2018
Dr Ed Schwalbe Dr Debbie Hicks Dr Reza Rafiee Dr Matthew Bashton Dr Amir Enshaei et al.	Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures	2017
Dr Ed Schwalbe Dr Janet Lindsey Dr Sirintra Nakjang Dr Stephen Crosier Amanda Smith et al.	Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study	2017
Dr Darren Smith Professor Nicholas Embleton Professor Janet Berrington Dr Ed Schwalbe Dr Clare Lanyon et al.	Reducing Viability Bias in Analysis of Gut Microbiota in Preterm Infants at Risk of NEC and Sepsis	2017
Dr Ed Schwalbe Dr Kevin Windebank Professor Stephen O'Brien Dr Peter Carey Professor Simon Bailey et al.	The use of anthracyclines in the treatment of endemic Burkitt lymphoma	2017
Dr Stephen Crosier Dr Debbie Hicks Dr Ed Schwalbe Dr Daniel Williamson Sarah Nicholson et al.	Centralised Molecular Pathology for Rare Tumours: A National Feasibility Study of Real-Time Medulloblastoma Diagnostics	2016
Dr Daniel Williamson Dr Janet Lindsey Dr Debbie Hicks Dr Stephen Crosier Amanda Smith et al.	The Transcriptional Landscape of Medulloblastoma: Group 3 and Group 4 Tumours Comprise a Single Clinically Significant Expression Continuum	2016
Professor Steven Clifford Dr Ed Schwalbe Dr Debbie Hicks Kieran O'Toole Sarah Nicholson et al.	Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial	2015
Dr Rebecca Hill Dr Janet Lindsey Dr Ed Schwalbe Dr Karen Barker Dr Daniel Williamson et al.	Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease	2015
Dr Ed Schwalbe Professor Steven Clifford	DNA Methylation Analysis of Paediatric Low-Grade Astrocytomas Identifies a Tumour-Specific Signature at a Set of Enhancers	2015
Dr Ed Schwalbe Dr Kevin Windebank Dr Peter Carey Professor Simon Bailey	The Role of Anthracyclines in the Treatment of Endemic Burkitt Lymphoma	2015
Dr Ed Schwalbe Dr Lucy Chilton	Glycerol and acetaminophen as adjuvant therapy did not affect the outcome of bacterial meningitis in Malawian children.	2014
Fadhel Alsaid Naji Dr Vikki Rand Professor Anthony Moorman Dr Ed Schwalbe Dr Amir Enshaei et al.	Investigation of methylation based biomarkers for prediction of relapse in good prognostic cytogenetic subgroups of childhood acute lymphoblastic leukaemia	2014
Dr Ed Schwalbe Dr Daniel Williamson Dr Janet Lindsey Dolores Hamilton Sarra Ryan et al.	DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies	2013
Dr Rebecca Hill Dr Janet Lindsey Dr Ed Schwalbe Professor Simon Bailey Professor Steven Clifford et al.	Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma	2013
Dr Sarra Ryan Dr Ed Schwalbe Mike Cole Yuan Lu Dr Meryl Lusher et al.	MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma	2012
Dr Ed Schwalbe Professor Steven Clifford	Genome-Wide Analysis of Alternative Splicing in Medulloblastoma Identifies Splicing Patterns Characteristic of Normal Cerebellar Development	2011