Dr Tarek Mamdouh Abdelghany Lanyu Fan Dr Satomi Miwa Dr Agnieszka Bronowska
| M8OI toxicity is associated with an inhibition of ubiquinone reduction by complex I in the mitochondrial electron transport chain | 2025 |
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Professor Katarina Novakovic Dr Wing Man Lau Dr Tarek Mamdouh Abdelghany
| Chitosan hydrogel based microneedle technology for prolonged release of actives | 2024 |
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Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany Dr Martin Cooke Professor Matt Wright
| Ionic Liquid 1-Octyl-3-Methylimidazolium (M8OI) Is Mono-Oxygenated by CYP3A4 and CYP3A5 in Adult Human Liver | 2024 |
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Dr Tarek Mamdouh Abdelghany Shireen Hedya Carol De Santis Dr Jason Gill Professor Matt Wright et al. | Potential for cardiac toxicity with methylimidazolium ionic liquids | 2023 |
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Shireen Hedya Dr Alex Charlton Dr Alistair Leitch Fahad Aljehani Professor Matt Wright et al. | The methylimidazolium ionic liquid M8OI is a substrate for OCT1 and p-glycoprotein-1 in rat | 2023 |
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Dr Alistair Leitch Dr Ibrahim Ibrahim Dr Tarek Mamdouh Abdelghany Dr Alex Charlton Clair Roper et al. | The methylimidazolium ionic liquid M8OI is detectable in human sera and is subject to biliary excretion in perfused human liver | 2021 |
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Dr Tarek Mamdouh Abdelghany Dr Alistair Leitch Professor Peter Blain Professor Matt Wright
| Changes in the gut microbiota of mice orally exposed to methylimidazolium ionic liquids | 2020 |
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Dr Tarek Mamdouh Abdelghany Dr Alistair Leitch Dr Ibrahim Ibrahim Dr Satomi Miwa Professor Colin Wilson et al. | Emerging risk from "environmentally-friendly" solvents: Interaction of methylimidazolium ionic liquids with the mitochondrial electron transport chain is a key initiation event in their mammalian toxicity | 2020 |
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Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany Dr Alex Charlton Professor Fiona Oakley Dr Lee Borthwick et al. | Renal injury and hepatic effects from the methylimidazolium ionic liquid M8OI in mouse | 2020 |
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Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany Dr Phillip Probert Dr Stephanie Meyer Dr Jeremy Palmer et al. | The toxicity of the methylimidazolium ionic liquids, with a focus on M8OI and hepatic effects | 2020 |
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Rachel Wilson Charlotte Candlish Dr Ibrahim Ibrahim Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany et al. | Expression of serine/threonine protein kinase SGK1F promotes an hepatoblast state in stem cells directed to differentiate into hepatocytes | 2019 |
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Dr Emma Fairhall Dr Alistair Leitch Anne Lakey Dr Tarek Mamdouh Abdelghany Dr Ibrahim Ibrahim et al. | HNF4alpha expression amplifies the glucocorticoid-induced conversion of a human pancreatic cell line to an hepatocyte-like cell | 2018 |
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Dr Phillip Probert Dr Alistair Leitch Dr Michael Dunn Dr Stephanie Meyer Dr Jeremy Palmer et al. | Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis | 2018 |
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