Publications by Dr Alistair Leitch - ePrints

Browsing publications by Dr Alistair Leitch.

Newcastle Authors	Title	Year
Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany Dr Martin Cooke Professor Matt Wright	Ionic Liquid 1-Octyl-3-Methylimidazolium (M8OI) Is Mono-Oxygenated by CYP3A4 and CYP3A5 in Adult Human Liver	2024
Dr Tarek Abdelghany Lanyu Fan Ben Air Dr Alistair Leitch Dr Martin Cooke et al.	Methylimidazolium ionic liquids - A new class of forever chemicals with endocrine disrupting potential	2024
Shireen Hedya Dr Alex Charlton Dr Alistair Leitch Fahad Aljehani Professor Matt Wright et al.	The methylimidazolium ionic liquid M8OI is a substrate for OCT1 and p-glycoprotein-1 in rat	2023
Rodrigo Figueiredo Dr Avinash Sewpaul Dr Alistair Leitch Lucy Bates Professor Matthew Wright et al.	Pregnane X Receptor Activation in Liver Perfusion	2022
Dr Alistair Leitch Dr Ibrahim Ibrahim Dr Tarek Mamdouh Abdelghany Dr Alex Charlton Clair Roper et al.	The methylimidazolium ionic liquid M8OI is detectable in human sera and is subject to biliary excretion in perfused human liver	2021
Dr Tarek Mamdouh Abdelghany Dr Alistair Leitch Professor Peter Blain Professor Matt Wright	Changes in the gut microbiota of mice orally exposed to methylimidazolium ionic liquids	2020
Dr Tarek Mamdouh Abdelghany Dr Alistair Leitch Dr Ibrahim Ibrahim Dr Satomi Miwa Professor Colin Wilson et al.	Emerging risk from "environmentally-friendly" solvents: Interaction of methylimidazolium ionic liquids with the mitochondrial electron transport chain is a key initiation event in their mammalian toxicity	2020
Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany Dr Alex Charlton Professor Fiona Oakley Dr Lee Borthwick et al.	Renal injury and hepatic effects from the methylimidazolium ionic liquid M8OI in mouse	2020
Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany Dr Phillip Probert Dr Stephanie Meyer Dr Jeremy Palmer et al.	The toxicity of the methylimidazolium ionic liquids, with a focus on M8OI and hepatic effects	2020
Rachel Wilson Charlotte Candlish Dr Ibrahim Ibrahim Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany et al.	Expression of serine/threonine protein kinase SGK1F promotes an hepatoblast state in stem cells directed to differentiate into hepatocytes	2019
Dr Emma Fairhall Dr Alistair Leitch Anne Lakey Dr Phillip Probert Carol De Santis et al.	Glucocorticoid-induced pancreatic-hepatic trans-differentiation in a human cell line in vitro	2018
Dr Emma Fairhall Dr Alistair Leitch Anne Lakey Dr Tarek Mamdouh Abdelghany Dr Ibrahim Ibrahim et al.	HNF4alpha expression amplifies the glucocorticoid-induced conversion of a human pancreatic cell line to an hepatocyte-like cell	2018
Dr Phillip Probert Dr Alistair Leitch Dr Michael Dunn Dr Stephanie Meyer Dr Jeremy Palmer et al.	Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis	2018
Dr Alistair Leitch Anne Lakey will Hotham Professor Loranne Agius Professor George Kass et al.	The ionic liquid 1-octyl-3-methylimidazolium (M8OI) is an activator of the human estrogen receptor alpha	2018
Dr Alistair Leitch Philip Probert Dr Stephanie Meyer Professor George Kass Professor Matthew Wright et al.	B-13 progenitor-derived hepatocytes (B-13/H cells) model lipid dysregulation in response to drugs and chemicals	2017
Dr Stephanie Meyer Dr Phillip Probert Anne Lakey Dr Alistair Leitch Dr Lynsay Blake et al.	Environmental xenoestrogens super-activate a variant murine ER beta in cholangiocytes	2017
Dr Stephanie Meyer Dr Phillip Probert Anne Lakey Andrew Axon Dr Alistair Leitch et al.	Hepatic effects of tartrazine (E 102) after systemic exposure are independent of oestrogen receptor interactions in the mouse	2017