Publications by Professor Matt Wright - ePrints

Browsing publications by Professor Matt Wright.

Newcastle Authors	Title	Year
Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany Dr Martin Cooke Professor Matt Wright	Ionic Liquid 1-Octyl-3-Methylimidazolium (M8OI) Is Mono-Oxygenated by CYP3A4 and CYP3A5 in Adult Human Liver	2024
Dr Tarek Abdelghany Lanyu Fan Ben Air Dr Alistair Leitch Dr Martin Cooke et al.	Methylimidazolium ionic liquids - A new class of forever chemicals with endocrine disrupting potential	2024
Shireen Hedya Adam Charlton Fahad Aljehani Khalid Alanazi Professor Matt Wright et al.	Undifferentiated HepaRG cells show reduced sensitivity to the toxic effects of M8OI through a combination of CYP3A7-mediated oxidation and a reduced reliance on mitochondrial function	2024
Dr Tarek Mamdouh Abdelghany Shireen Hedya Carol De Santis Dr Jason Gill Professor Matt Wright et al.	Potential for cardiac toxicity with methylimidazolium ionic liquids	2023
Shireen Hedya Dr Alex Charlton Dr Alistair Leitch Fahad Aljehani Professor Matt Wright et al.	The methylimidazolium ionic liquid M8OI is a substrate for OCT1 and p-glycoprotein-1 in rat	2023
Dr Alistair Leitch Dr Ibrahim Ibrahim Dr Tarek Mamdouh Abdelghany Dr Alex Charlton Clair Roper et al.	The methylimidazolium ionic liquid M8OI is detectable in human sera and is subject to biliary excretion in perfused human liver	2021
Dr Tarek Mamdouh Abdelghany Dr Alistair Leitch Professor Peter Blain Professor Matt Wright	Changes in the gut microbiota of mice orally exposed to methylimidazolium ionic liquids	2020
Dr Tarek Mamdouh Abdelghany Dr Alistair Leitch Dr Ibrahim Ibrahim Dr Satomi Miwa Professor Colin Wilson et al.	Emerging risk from "environmentally-friendly" solvents: Interaction of methylimidazolium ionic liquids with the mitochondrial electron transport chain is a key initiation event in their mammalian toxicity	2020
Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany Dr Alex Charlton Professor Fiona Oakley Dr Lee Borthwick et al.	Renal injury and hepatic effects from the methylimidazolium ionic liquid M8OI in mouse	2020
Rachel Wilson Charlotte Candlish Dr Ibrahim Ibrahim Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany et al.	Expression of serine/threonine protein kinase SGK1F promotes an hepatoblast state in stem cells directed to differentiate into hepatocytes	2019
Dr Emma Fairhall Dr Alistair Leitch Anne Lakey Dr Tarek Mamdouh Abdelghany Dr Ibrahim Ibrahim et al.	HNF4alpha expression amplifies the glucocorticoid-induced conversion of a human pancreatic cell line to an hepatocyte-like cell	2018
Dr Emma Fairhall Dr Karen Wallace Steven White Professor James Shaw Professor Alastair Burt et al.	Adult human exocrine pancreas differentiation to hepatocytes – potential source of a human hepatocyte progenitor for use in toxicology research	2013