Publications by Professor Nikolay Zenkin - ePrints

Browsing publications by Professor Nikolay Zenkin.

Newcastle Authors	Title	Year
Dr Jason Woodgate Felaine Sumang Mary Salliss Emeritus Professor Alan Ward Professor Nikolay Zenkin et al.	Mode of Action and Mechanisms of Resistance to the Unusual Polyglycosylated Thiopeptide Antibiotic Persiathiacin A	2025
Dr Jason Woodgate Dr Hamed Mosaei Sejzi Dr Pavel Brazda Dr Flint Stevenson-Jones Professor Nikolay Zenkin et al.	Translation selectively destroys non-functional transcription complexes	2024
Dr Jason Woodgate Professor Nikolay Zenkin	Transcription–translation coupling: Recent advances and future perspectives	2023
Professor Nikolay Zenkin	Complex genetic interactions between piwi and hp1a in the repression of transposable elements and tissue‐specific genes in the ovarian germline	2021
John Harbottle Dr Hamed Mosaei Sejzi Dr Nicholas Allenby Professor Nikolay Zenkin	Kanglemycin a can overcome rifamycin resistance caused by adp-ribosylation by arr protein	2021
Dr Soren Nielsen Professor Nikolay Zenkin	Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription	2021
Dr Hamed Mosaei Sejzi Professor Nikolay Zenkin	Two distinct pathways of RNA polymerase backtracking determine the requirement for the Trigger Loop during RNA hydrolysis	2021
Caitlin Griffiths Dr Hamed Mosaei Sejzi Professor Nikolay Zenkin	Evolving MRSA: High-level β-lactam resistance in Staphylococcus aureus is associated with RNA Polymerase alterations and fine tuning of gene expression	2020
Dr Hamed Mosaei Sejzi Professor Nikolay Zenkin	Inhibition of RNA Polymerase by Rifampicin and Rifamycin-Like Molecules	2020
Dr Flint Stevenson-Jones Dr Jason Woodgate Daniel Castro-Roa Professor Nikolay Zenkin	Ribosome reactivates transcription by physically pushing RNA polymerase out of transcription arrest	2020
John Harbottle Professor Nikolay Zenkin	Ureidothiophene inhibits interaction of bacterial RNA polymerase with -10 promotor element	2020
Dr Bernhard Kepplinger Professor Nikolay Zenkin Dr Michael Hall Dr Nicholas Allenby	Compounds for Treating Infections Caused by Rifampicin-resistant Bacteria	2018
Dr Hamed Mosaei Sejzi Dr Bernhard Kepplinger John Harbottle Lucia Ceccaroni Ceccaroni Dr Stephanie Morton-Laing et al.	Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin Resistant Mycobacterium tuberculosis	2018
Daniel Castro-Roa Professor Nikolay Zenkin	Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors	2018
Dr Pamela Gamba Professor Nikolay Zenkin	Transcription fidelity and its roles in the cell	2018
Dr Pamela Gamba Dr Katherine James Professor Nikolay Zenkin	A link between transcription fidelity and pausing in vivo	2017
Dr Katherine James Dr Simon Cockell Professor Nikolay Zenkin	Deep sequencing approaches for the analysis of prokaryotic transcriptional boundaries and dynamics	2017
Dr Katherine James Dr Pamela Gamba Dr Simon Cockell Professor Nikolay Zenkin	Misincorporation by RNA polymerase is a major source of transcription pausing in vivo	2017
Dr David Forrest Dr Katherine James Dr Yulia Yuzenkova Professor Nikolay Zenkin	Single-peptide DNA-dependent RNA polymerase homologous to multi-subunit RNA polymerase	2017
Andrew Tyler Dr Hamed Mosaei Sejzi Stephanie Morton Dr Paul Waddell Dr Corinne Wills et al.	Structural Reassignment and Absolute Stereochemistry of Madurastatin C1 (MBJ-0034) and the Related Aziridine Siderophores: Madurastatins A1, B1 and MBJ-0035	2017
Dr Robert van Nues Daniel Castro-Roa Dr Yulia Yuzenkova Professor Nikolay Zenkin	Ribonucleoprotein particles of bacterial small non-coding RNA IsrA (IS61 or McaS) and its interaction with RNA polymerase core may link transcription to mRNA fate	2016
Dr Mohammad Roghanian Professor Nikolay Zenkin Dr Yulia Yuzenkova	Bacterial global regulators DksA/ppGpp increase fidelity of transcription	2015
Professor Nikolay Zenkin Dr Yulia Yuzenkova	Bacteriophage Xp10 anti-termination factor p7 induces forward translocation by host RNA polymerase	2015
Daniel Castro-Roa Professor Nikolay Zenkin	Methodology for the analysis of transcription and translation in transcription-coupled-to-translation systems in vitro	2015
Dr Daniel Castro Roa Professor Nikolay Zenkin	Methods for the Assembly and Analysis of In Vitro Transcription-Coupled-to-Translation Systems	2015
Professor Nikolay Zenkin Dr Yulia Yuzenkova	New Insights into the Functions of Transcription Factors that Bind the RNA Polymerase Secondary Channel	2015
Professor Nikolay Zenkin	Ancient RNA stems that terminate transcription	2014
Savva Zorov Dr Yulia Yuzenkova Professor Nikolay Zenkin	Antibiotic streptolydigin requires non-catalytic Mg²⁺ for binding to RNA polymerase	2014
Dr Yulia Yuzenkova Dr Pamela Gamba Professor Nikolay Zenkin Dr Jan-Willem Veening	Control of transcription elongation by GreA determines rate of gene expression in Streptococcus pneumoniae	2014
Professor Nikolay Zenkin	Multiple personalities of the RNA polymerase active centre	2014
Dr Yulia Yuzenkova Professor Nikolay Zenkin	Optimized delivery of fluorescently labeled proteins in live bacteria using electroporation	2014
Dr Soren Nielsen Professor Nikolay Zenkin	Response to Comment on "Mechanism of eukaryotic RNA polymerase III transcription termination"	2014
Professor Nikolay Zenkin	RNA secondary structure-dependent termination of transcription	2014
Professor Nikolay Zenkin	The many faces of Fic: structural and functional aspects of Fic enzymes	2014
Dr Soren Nielsen Dr Yulia Yuzenkova Professor Nikolay Zenkin	Mechanism of Eukaryotic RNA Polymerase III Transcription Termination	2013
Professor Nikolay Zenkin	Mitochondrial translation initiation machinery: Conservation and diversification	2013
Dr Elsa Germain - Maisonneuve Dr Daniel Castro Roa Professor Nikolay Zenkin Professor Kenn Gerdes	Molecular Mechanism of Bacterial Persistence by HipA	2013
Professor Nikolay Zenkin	Protein biosynthesis in mitochondria	2013
Dr Yulia Yuzenkova Dr Mohammad Roghanian Dr Aleksandra Bochkareva Professor Nikolay Zenkin	Tagetitoxin inhibits transcription by stabilizing pre-translocated state of the elongation complex	2013
Daniel Castro-Roa Professor Nikolay Zenkin	The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu	2013
Dr Daniel Castro Roa Professor Nikolay Zenkin	The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu	2013
Dr Aleksandra Bochkareva Professor Nikolay Zenkin	The sigma70 region 1.2 regulates promoter escape by unwinding DNA downstream of the transcription start site	2013
Dr Soren Nielsen Professor Nikolay Zenkin	Transcript assisted phosphodiester bond hydrolysis by eukaryotic RNA polymerase II	2013
Dr Aleksandra Bochkareva Dr Yulia Yuzenkova Professor Nikolay Zenkin	Factor-independent transcription pausing caused by recognition of the RNA-DNA hybrid sequence	2012
Professor Nikolay Zenkin	Hypothesis: Emergence of Translation as a Result of RNA Helicase Evolution	2012
Dr Daniel Castro Roa Professor Nikolay Zenkin	In vitro experimental system for analysis of transcription-translation coupling	2012
Dr Yulia Yuzenkova Dr Mohammad Roghanian Professor Nikolay Zenkin	Multiple active centers of multi-subunit RNA polymerases	2012
Dr Yulia Yuzenkova Professor Nikolay Zenkin	A new basal promoter element recognized by RNA polymerase core enzyme	2011
Dr Mohammad Roghanian Dr Yulia Yuzenkova Professor Nikolay Zenkin	Controlled interplay between trigger loop and Gre factor in the RNA polymerase active centre	2011
Dr Daniel Castro Roa Professor Nikolay Zenkin	Relations Between Replication and Transcription	2011
Dr Yulia Yuzenkova Professor Nikolay Zenkin	Central role of the RNA polymerase trigger loop in intrinsic RNA hydrolysis	2010
Dr Yulia Yuzenkova Dr Aleksandra Bochkareva Dr Mohammad Roghanian Professor Nikolay Zenkin	Stepwise mechanism for transcription fidelity	2010
Dr Yulia Yuzenkova Professor Nikolay Zenkin	Mapping of RNA Polymerase Residues that Interact with Bacteriophage Xp10 Transcription Antitermination Factor p7	2008
Professor Nikolay Zenkin	RNA polymerase - The third class of primases	2008
Professor Nikolay Zenkin Dr Yulia Yuzenkova	Region 1.2 of the RNA polymerase sigma subunit controls recognition of the -10 promoter element	2007
Professor Nikolay Zenkin	The mechanism of DNA replication primer synthesis by RNA polymerase	2006
Professor Nikolay Zenkin Dr Yulia Yuzenkova	Transcript-Assisted Transcriptional Proofreading	2006
Professor Nikolay Zenkin	Structural Basis of Transcription Inhibition by Antibiotic Streptolydigin	2005
Professor Nikolay Zenkin	The role of RNA polymerase σ subunit in promoter-independent initiation of transcription	2004