Publications by Dr Linda Hogarth - ePrints

Browsing publications by Dr Linda Hogarth.

Newcastle Authors	Title	Year
Dr Abi Gault Dr Linda Hogarth Dr Kristian Williams Professor Alastair Greystoke Professor Neil Rajan et al.	Monitoring immunE DysregulAtion foLLowing Immune checkpOint-inhibitioN (MEDALLION): protocol for an observational cancer immunotherapy cohort study	2024
Sarah Rae Dr Linda Hogarth Alison Bridgewood Lisa Brown-Schofield Dr Saira Bashir et al.	Prevalence of mutations in common tumour types in Northern England and comparable utility of national and international Trial Finders	2023
Dr Nicola Wyatt Dr Linda Hogarth Dianne Turner Dr Miranda Patterson Dr David Jamieson et al.	Circulating Biomarkers of Frailty Are Associated with a Poor Prognosis in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC)	2016
Professor Alastair Greystoke Dr Linda Hogarth Dr Miranda Patterson Liam Bolt Dianne Turner et al.	The introduction of the Cancer Research UK Stratified Medicine Programme 2 (CRUK SMP2) in North East England; lessons learned and experience gained	2016
Dr Linda Hogarth Dr Andrew Hall	p21^WAF1 modulates drug-induced apoptosis and cell cycle arrest in B-cell precursor acute lymphoblastic leukemia	2015
Dr Nicola Cresti Dr Linda Hogarth	Phase I expansion of S-222611, a reversible inhibitor of EGFR and HER2, in advanced solid tumors, including patients with brain metastases.	2015
Dr Sally Coulthard Dr Chris Redfern Svante Vikingsson Dr Malin Lindqvist Appell Dr Andrew Hall et al.	Increased Sensitivity to Thiopurines in Methylthioadenosine Phosphorylase-Deleted Cancers	2011
Dr Linda Hogarth Dr Andrew Hall	p53-independent Epigenetic Repression of the p21^WAF1 Gene in T-cell Acute Lymphoblastic Leukemia	2011
Dr Sally Coulthard Dr Chris Redfern Dr Linda Hogarth	Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers [abstract]	2010
Dr Linda Hogarth Dr Chris Redfern Dr Andrew Hall Dr Holly Anderson Marian Case et al.	The effect of thiopurine drugs on DNA methylation in relation to TPMT expression	2008
Elizabeth Matheson Dr Linda Hogarth Marian Case Professor Julie Irving Dr Andrew Hall et al.	DHFR and MSH3 co-amplification in childhood acute lymphoblastic leukaemia, in vitro and in vivo	2007
Marian Case Dr Andrew Hall Dr Linda Hogarth Amanda Jones	Design, synthesis and initial in vitro evaluation of novel prodrugs for the treatment of cystinosis	2006
Professor Nick Reynolds Dr Helen Anderson Gordon Taylor Dr Andrew Hall Dr Linda Hogarth et al.	Thioguanine nucleotide levels correlate with clinical response in atopic eczema patients treated with azathioprine	2006
Dr Simon Meggitt Professor Nick Reynolds Dr Helen Anderson Gordon Taylor Dr Andrew Hall et al.	Thioguanine nucleotides in patients with moderate-to-severe atopic eczema treated with azathioprine	2006
Professor Julie Irving Clare Bloodworth Dr Nicholas Bown Marian Case Dr Linda Hogarth et al.	Loss of heterozygosity in childhood acute lymphoblastic leukemia detected by genome-wide microarray single nucleotide polymorphism analysis	2005
Dr Sally Coulthard Dr Linda Hogarth	The thiopurines: An update	2005
Dr Andrew Hall Clare Bloodworth Dr Linda Hogarth Dr Nicholas Bown Professor Julie Irving et al.	Loss of heterozygosity in childhood acute lymphoblastic leukaemia detected by genome-wide microarray single nucleotide polymorphism analysis	2004
Dr Sally Coulthard Dr Linda Hogarth	Old drugs-current perspectives	2004
Dr Sally Coulthard Dr Andrew Hall Dr Linda Hogarth	The clinical impact of thiopurine methyltransferase polymorphisms on thiopurine treatment	2004
Clare Bloodworth Dr Linda Hogarth Dr Andrew Hall	Role of mismatch repair in determining sensitivity to the topoisomerase II poisons	2003
Dr Linda Hogarth Dr Sally Coulthard Dr Andrew Hall Lindi Skitt	The effect of thiopurine methyltransferase on the cytotoxic action of thiopurine drugs	2003
Dr Sally Coulthard Dr Linda Hogarth Dr Margaret Little Elizabeth Matheson Dr Chris Redfern et al.	The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs	2002
Dr Linda Hogarth Lynne Minto	Enhanced expression and activity of DNA polymerase β in human ovarian tumor cells: impact on sensitivity towards antitumor agents	2001
Dr Linda Hogarth Dr Margaret Little Lynne Minto Dr Chris Redfern Dr Andrew Hall et al.	High thiopurine methyltransferase expression confers different levels of resistance with 6-thioguanine compared to 6-mercaptopurine.	2001
Dr Linda Hogarth Dr Margaret Little Lynne Minto Dr Chris Redfern Dr Andrew Hall et al.	In vitro evidence for differences in 6-mercaptopurine versus 6-thioguanine metabolism depending on TPMT status	2001
Dr Sally Coulthard Dr Linda Hogarth Lynne Minto Dr Chris Redfern Dr Andrew Hall et al.	High thiopurine methyltransferase expression confers different levels of resistance with 6-thioguanine compared to 6-mercaptopurine	2000
Dr Linda Hogarth Elizabeth Matheson Lynne Minto Dr Margaret Little Dr Andrew Hall et al.	Measurement of resistance to thiopurine drugs in cells with defective mismatch repair	2000
Dr Linda Hogarth Dr Andrew Hall	Increased BAX expression is associated with an increased risk of relapse in childhood acute lymphocytic leukemia	1999
Dr Andrew Hall Dr Linda Hogarth	Sensitivity of testis tumour cells to chemotherapeutic drugs: Role of detoxifying pathways	1996
Dr Linda Hogarth Professor Andrew Pearson Dr Andrew Hall	The effect of treatment with high dose melphalan, cisplatin or carboplatin on levels of glutathione in plasma, erythrocytes, mononuclear cells and urine	1996
Dr Andrew Hall Elizabeth Matheson Dr Linda Hogarth	Purification of an alpha class glutathione S-transferase from melphalan-resistant Chinese hamster ovary cells and demonstration of its ability to catalyze melphalan-glutathione adduct formation	1994
Dr Linda Hogarth Dr Michael Reid Professor Stephen Proctor Dr Peter Hamilton Dr Andrew Hall et al.	Raised intracellular glutathione levels correlate with in vitro resistance to cytotoxic drugs in leukaemic cells from patients with acute lymphoblastic leukaemia	1994
Dr Linda Hogarth Dr Andrew Hall	Cytosolic glutathione (GSH) levels of leukemic blasts in relation to in vitro anthracycline resistance	1993