Publications by Elizabeth Matheson - ePrints

Browsing publications by Elizabeth Matheson.

Newcastle Authors	Title	Year
Lucy Gentles Bojidar Goranov Elizabeth Matheson Dr Ashleigh Herriott Dr Angelika Kaufmann et al.	Exploring the frequency of Homologous Recombination DNA Repair Dysfunction in Multiple Cancer Types	2019
Zach Dixon Dr Lindsay Nicholson Elizabeth Matheson Dr Paul Sinclair Professor Christine Harrison FRCPath FMedSci et al.	CREBBP knockdown enhances RAS/RAF/MEK/ERK signaling in Ras pathway mutated acute lymphoblastic leukemia but does not modulate chemotherapeutic response	2017
Professor Julie Irving Dr Amir Enshaei Dr Amy Erhorn Lynne Minto Claire Schwab et al.	Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukaemia	2016
Dr Ganiy Abdulrahman Elizabeth Matheson Dr Yvette Drew Professor Nicola Curtin Dr Asima Mukhopadhyay et al.	Investigating PARP inhibitor sensitisation by hyperthermia and HSP90 inhibition	2016
Elizabeth Matheson Dr Mo Salehan Dr Asima Mukhopadhyay Professor Nicola Curtin Dr Yvette Drew et al.	Preclinical studies of the PARP inhibitor olaparib in combination with imatinib in BRCA stratified ovarian cancer	2016
Dr Sarra Ryan Elizabeth Matheson Dr Paul Sinclair Dr Matthew Bashton Claire Schwab et al.	The role of the RAS pathway in iAMP21-ALL	2016
Dr Lindsay Nicholson Elizabeth Matheson Lynne Minto Christopher Keilty Maryna Sanichar et al.	Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition	2015
Professor Julie Irving Elizabeth Matheson Helen Blair Marian Case Isabella Swidenbank et al.	Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition. Blood. 2014;124(23):3420-3430	2015
Professor Julie Irving Elizabeth Matheson Dr Helen Blair Marian Case Isabella Swidenbank et al.	Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition	2014
Dr Lindsay Nicholson Elizabeth Matheson Lynne Minto Marian Case Maryna Sanichar et al.	Casitas B lymphoma mutations in childhood acute lymphoblastic leukemia	2012
Dr Lindsay Nicholson Charlotte Evans Elizabeth Matheson Lynne Minto Christopher Keilty et al.	Quantitative Proteomic Analysis Reveals Maturation As a Mechanism Underlying Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia and PAX5 As a Re-Sensitising Therapeutic Target	2011
Dr Sarra Ryan Dr Vikki Rand Claire Schwab Heather Morrison Elizabeth Matheson et al.	Ras Signalling Pathway and Novel Target Genes Related to Down Syndrome Contribute to the Development of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) in iAMP21 Patients	2011
Dr Amy Peasland Elizabeth Matheson Dr Andrew Hall Professor Julie Irving	Alternative splicing of hMLH1 in childhood acute lymphoblastic leukaemia and characterisation of the variably expressed Δ9/10 isoform as a dominant negative species	2010
Elizabeth Matheson Lynne Minto Dr Andrew Hall Professor Julie Irving	Mismatch repair and the downstream target genes, PAX5 and Ikaros, in childhood acute lymphoblastic leukemia	2010
Dr Lindsay Nicholson Elizabeth Matheson Lynne Minto Christopher Keilty Dr Andrew Hall et al.	Quantitative Proteomic Analysis Implicates An Altered B-Cell Differentiation State as a Mechanism Underlying GC-Resistance in An Acute Lymphoblastic Leukaemia (ALL) Cell Line Model	2009
Elizabeth Matheson Lynne Minto Professor Anthony Moorman Dr Andrew Hall Professor Julie Irving et al.	Heterogeneous breakpoints target PAX5 in acute lymphoblastic leukaemia patients with dicentric chromosomes	2008
Elizabeth Matheson Mike Cole Dr Bridget Wilkins Dr Andrew Hall	Mismatch repair defects in childhood acute lymphoblastic leukaemia at diagnosis and relapse	2008
Marian Case Elizabeth Matheson Lynne Minto Dr Nicholas Bown Professor Simon Bailey et al.	Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia	2008
Marian Case Elizabeth Matheson Lynne Minto Professor Christine Harrison FRCPath FMedSci Dr Nicholas Bown et al.	Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting	2008
Elizabeth Matheson Professor Anthony Moorman Dr Andrew Hall Professor Christine Harrison FRCPath FMedSci Professor Julie Irving et al.	Variable breakpoints target PAX5 in patients with dicentric chromosomes: A model for the basis of unbalanced translocations in cancer	2008
Elizabeth Matheson Dr Linda Hogarth Marian Case Professor Julie Irving Dr Andrew Hall et al.	DHFR and MSH3 co-amplification in childhood acute lymphoblastic leukaemia, in vitro and in vivo	2007
Elizabeth Matheson Lynne Minto Professor Anthony Moorman Dr Andrew Hall Professor Julie Irving et al.	Variable Breakpoints Target PAX5 in Patients with Dicentric Chromosomes: A Model for the Basis of Unbalanced Translocations in Cancer	2007
Professor Julie Irving Lynne Minto Elizabeth Matheson Dr Lindsay Nicholson Dr Andrew Hall et al.	Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor	2006
Professor Julie Irving Lynne Minto Elizabeth Matheson Marian Case Professor Simon Bailey et al.	Mutation in genes impacting on the RAS-RAF-MEK-ERK pathway are found at high incidence in childhood acute lymphoblastic leukemia at both diagnosis and at relapse.	2006
Dr Mark Velangi Elizabeth Matheson Dr Andrew Hall Professor Julie Irving	Detecting mismatch repair defects in myeloma	2005
Dr Mark Velangi Elizabeth Matheson Dr Penelope Taylor Professor Graham Jackson Dr Andrew Hall et al.	BRAF gene is not mutated in mismatch repair-proficient or -deficient plasma cell dyscrasias	2004
Dr Mark Velangi Elizabeth Matheson Professor Graham Jackson Dr Penelope Taylor Dr Andrew Hall et al.	DNA mismatch repair pathway defects in the pathogenesis and evolution of myeloma	2004
Elizabeth Matheson Dr Andrew Hall	Assessment of mismatch repair function in leukaemic cell lines and blasts from children with acute lymphoblastic leukaemia	2003
Elizabeth Matheson Dr Andrew Hall	Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX	2003
Penelope Mason Elizabeth Matheson Dr Andrew Hall Professor Robert Lightowlers	Mismatch repair activity in mammalian mitochondria	2003
Dr Andrew Hall Elizabeth Matheson	Mismatch repair defects in acute lymphoblastic leukaemia	2003
Dr Sally Coulthard Dr Linda Hogarth Dr Margaret Little Elizabeth Matheson Dr Chris Redfern et al.	The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs	2002
Elizabeth Matheson Dr Andrew Hall	Drug discovery - High throughput automated 2-D gel analysis - Tutorial: Proteomic analysis with nonlinear dynamics' progenesis image analysis software	2001
Dr Linda Hogarth Elizabeth Matheson Lynne Minto Dr Margaret Little Dr Andrew Hall et al.	Measurement of resistance to thiopurine drugs in cells with defective mismatch repair	2000
Dr Michael Reid Elizabeth Matheson Dr Penelope Taylor Professor Stephen Proctor Dr Andrew Hall et al.	Corticosteroid resistance is increased in lymphoblasts from adults compared with children: preliminary results of in vitro drug sensitivity study in adults with acute lymphoblastic leukaemia	1995
Dr Andrew Hall Elizabeth Matheson Dr Linda Hogarth	Purification of an alpha class glutathione S-transferase from melphalan-resistant Chinese hamster ovary cells and demonstration of its ability to catalyze melphalan-glutathione adduct formation	1994