Dr Anja Krippner-Heidenreich
| TNF-α–induced protein 3 (TNFAIP3)/A20 acts as a master switch in TNF-α blockade–driven IL-17A expression | 2018 |
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Zak Gamie Dr Emma Haagensen Ricardo da Conceicao Ribeiro Professor Kenneth Dalgarno Dr Anja Krippner-Heidenreich et al. | TNF-related apoptosis-inducing ligand (TRAIL) for bone sarcoma treatment: Pre-clinical and clinical data | 2017 |
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Marilena Patsalidou Dr Amy Anderson Dr Anja Krippner-Heidenreich
| An unconventional anti-inflammatory role for TNF recpetor (TNFR)1 in tregs: TNFR1 and 2 differetnialy modulate FOXP3+ TREG function | 2014 |
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Dr Nicola Maney Dr Gary Reynolds Dr Anja Krippner-Heidenreich Professor Catharien Hilkens
| Dendritic Cell Maturation and Survival Are Differentially Regulated by TNFR1 and TNFR2 | 2014 |
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Professor Jaap van Laar Dr Anja Krippner-Heidenreich
| CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex | 2013 |
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Dr Thomas Huegle Dr Steven O'Reilly Rachel Simpson Dr Venetia Bigley Professor Matthew Collin et al. | Tumor Necrosis Factor-Costimulated T Lymphocytes From Patients With Systemic Sclerosis Trigger Collagen Production in Fibroblasts | 2013 |
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Dr Steven O'Reilly Dr Bridget Griffiths Dr Anja Krippner-Heidenreich Professor Jaap Van Laar
| T cell derived IL-6 and IL-13 drive fibroblast fibrosis: Implications for systemic sclerosis | 2012 |
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Dr Aaron Ions Gardner Professor Andrew Fisher Christine Richter Grace Johnson Dr Elizabeth Moisey et al. | The Critical Role of TAK1 in Accentuated Epithelial to Mesenchymal Transition in Obliterative Bronchiolitis after Lung Transplantation | 2012 |
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Simon Neumann Dr Anja Krippner-Heidenreich
| The Transmembrane Domains of TNF-Related Apoptosis-Inducing Ligand (TRAIL) Receptors 1 and 2 Co-Regulate Apoptotic Signaling Capacity | 2012 |
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Christine Richter Professor Derek Mann Dr Anja Krippner-Heidenreich
| The Tumor Necrosis Factor Receptor Stalk Regions Define Responsiveness to Soluble versus Membrane-Bound Ligand | 2012 |
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Dr Steven O'Reilly Dr Venetia Bigley Professor Matthew Collin Dr Anja Krippner-Heidenreich Professor Jaap van Laar et al. | Tumor necrosis factor-alpha co-activated T-cells support a profibrotic cytokine milieu on cost of IL-10 expression in patients with systemic sclerosis | 2012 |
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Dr Anja Krippner-Heidenreich
| Analysis of ligand receptor interaction with new single chain TNF derivatives | 2011 |
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Dr Anja Krippner-Heidenreich
| Ligand-induced internalization of TNF receptor 2 mediated by a di-leucin motif is dispensable for activation of the NFκB pathway | 2011 |
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Dr Steven O'Reilly Dr Thomas Huegle Dr Anja Krippner-Heidenreich Professor Jaap Van Laar
| T cell-derived IL-6 and IL-13 drive dermal fibrosis: implications for systemic sclerosis | 2011 |
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Dr Anja Krippner-Heidenreich
| The stalk region of the TNF receptors highly determines soluble TNF responsiveness | 2011 |
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Dr Thomas Huegle Dr Anja Krippner-Heidenreich Rachel Simpson Dr Steven O'Reilly Dr Venetia Bigley et al. | Tumour necrosis factor alpha receptor activated T cells of patients with systemic sclerosis are deficient in IL-10 expression but promote myofibroblast differentiation via IL-6 and TGF-beta | 2011 |
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Dr Anja Krippner-Heidenreich
| Dual function of cysteine rich domain (CRD) 1 of TNF receptor type 1: conformational stabilization of CRD2 and control of receptor responsiveness | 2010 |
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Dr Anja Krippner-Heidenreich
| Fluorescence correlation spectroscopy reveals topological segregation of the two tumor necrosis factor membrane receptors | 2010 |
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Dr Anja Krippner-Heidenreich
| Potent antitumoral activity of TRAIL through generation of tumor-targeted single-chain fusion proteins | 2010 |
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Dr Nicola Maney Helen Baldwin Dr Anja Krippner-Heidenreich Professor Catharien Hilkens
| Regulation of dendritic cell survival and function by tumour necrosis factor receptors 1 and 2 | 2010 |
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Dr Anja Krippner-Heidenreich
| Single chain TNF derivatives with individually mutated receptor binding sites reveal differential stoichiometry of ligand receptor complex formation for TNFR1 and TNFR2 | 2010 |
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Dr Anja Krippner-Heidenreich
| Nanoscale Arrangement of Apoptotic Ligands Reveals a Demand for a Minimal Lateral Distance for Efficient Death Receptor Activation | 2009 |
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Dr Anja Krippner-Heidenreich Dr Jason Gill
| Single-Chain TNF, a TNF Derivative with Enhanced Stability and Antitumoral Activity | 2008 |
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Dr Anja Krippner-Heidenreich
| Tumour necrosis factors (review) | 2007 |
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Dr Anja Krippner-Heidenreich
| Caspase-dependent cleavage and subcellular redistribution of YY1 during apoptosis enhances proapoptotitic activity | 2005 |
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Dr Anja Krippner-Heidenreich
| The Met196Arg variation of human TNFR2 affects TNF-induced apoptosis by impaired NF-B-signalling and target gene expression | 2005 |
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Dr Anja Krippner-Heidenreich
| TNF-Funtionalized nanostructured particles for the stimulation of Membrane TNF-specific Cell responses | 2005 |
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Dr Anja Krippner-Heidenreich
| [reviwe] FasL and Fas: typical members of the TNF ligand and receptor family | 2004 |
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Dr Anja Krippner-Heidenreich
| Control of receptor-induced signaling complex formation by the kinetics of ligand/receptor interaction | 2002 |
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Dr Anja Krippner-Heidenreich
| Targeting of the transcription factor Max during apoptosis: phosphorylation-regulated cleavage by caspase-5 at an unusual glutamic acid residue in position P1 | 2001 |
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Dr Anja Krippner-Heidenreich
| Inhibition of proliferation and apoptosis by the transcriptional repressor Mad1: Repression of Fas-induced caspase-8 activation | 2000 |
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