Publications by Dr Jonathan Coxhead - ePrints

Browsing publications by Dr Jonathan Coxhead.

Newcastle Authors	Title	Year
Hannah Smith Francesco Kumara Mastrorosa Dr Giles Holt Dr Brendan Houston Dr Bilal Alobaidi et al.	A de novo paradigm for male infertility	2022
Dr Paul Donaghy Dr Simon Cockell Dr Carmen Martin-Ruiz Dr Jonathan Coxhead Dr Joseph Kane et al.	Blood mRNA expression in Alzheimer’s disease and dementia with Lewy bodies	2022
Andrea Masi Dr Chris Lamb Dr Simon Cockell Dr Jonathan Coxhead Professor Nicholas Embleton et al.	Distinct gene expression profiles between human preterm- and adult-derived intestinal organoids exposed to Enterococcus faecalis: A pilot study	2022
Dr Angela Pyle Dr Helen Griffin Dr Jonathan Coxhead Raf Hussain Dr Gavin Hudson et al.	Heteroplasmic mitochondrial DNA variants in cardiovascular diseases	2022
Dr Deepali Pal Dr Helen Blair Sean Hockney Dr Melanie Beckett Mankaran Singh et al.	hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia	2022
Dr Agata Rozanska Rodrigo Cerna Chavez Dr Rachel Queen Dr Joseph Collin Dr Darin Zerti et al.	pRB-depleted pluripotent stem cell retinal organoids recapitulate cell state transitions of retinoblastoma development and suggest an important role for pRB in retinal cell differentiation	2022
Dr Marina Danilenko Dr Claire Keeling Dr Stephen Crosier Dr Martina Finetti Dr Daniel Williamson et al.	Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development	2022
Ramada Khasawneh Dr Ralf Kist Dr Rachel Queen Raf Hussain Dr Jonathan Coxhead et al.	Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype	2021
Dr Laura Jardine Dr Simone Webb Issac Goh Dr Gary Reynolds Dr Michael Mather et al.	Blood and immune development in human fetal bone marrow and Down syndrome	2021
Catherine Hatton Dr Rachel Botting Dr Maria Duenas Fadic Dr Iram Haq Dr Bernard Verdon et al.	Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2	2021
Dr Gary Reynolds Dr Peter Vegh Dr James Fletcher Dr Beth Poyner Emily Stephenson et al.	Developmental cell programs are co-opted in inflammatory skin disease	2021
Emily Stephenson Dr Gary Reynolds Dr Rachel Botting Justin Engelbert Dr Bayanne Olabi et al.	Single-cell multi-omics analysis of the immune response in COVID-19	2021
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Maria Georgiou et al.	Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface	2020
Dr Hannah Lowes Dr Fiona Robertson Dr Angela Pyle Raf Hussain Dr Jonathan Coxhead et al.	The Human Coronavirus Receptor ANPEP (CD13) Is Overexpressed in Parkinson's Disease	2020
Dr Joseph Collin Dr Darin Zerti Dr Rachel Queen Dr Roman Bauer Dr Jonathan Coxhead et al.	CRX Expression in Pluripotent Stem Cell‐Derived Photoreceptors Marks a Transplantable Subpopulation of Early Cones	2019
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Raf Hussain et al.	Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina	2019
Dr Kirsty Hodgson Dr Ed Schwalbe Dr Jonathan Coxhead Naomi Sinclair Dr Simon Cockell et al.	Epigenetic modifiers DNMT3A and BCOR are recurrently mutated in CYLD cutaneous syndrome	2019
Dr Christopher Duncan Angela Grainger Andrew Skelton Raf Hussain Dr Joe Willet et al.	Early-onset autoimmune disease due to a heterozygous loss-of-function mutation in TNFAIP3 (A20)	2018
Dr Lauren Walker Dr Jonathan Coxhead Dr Ian Wilson Dr Matthew Bashton Dr Christopher Morris et al.	High prevalence of focal and multi-focal somatic genetic variants in the human brain	2018
Dr Vasileios Floros Dr Angela Pyle Dr Wei Wei Dr Brendan Payne Dr Jonathan Coxhead et al.	Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos	2018
Dr Michael Keogh Dr Wei Wei Dr Ian Wilson Dr Jonathan Coxhead Dr Helen Griffin et al.	Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource	2017
Dr Michael Keogh Dr Ian Wilson Dr Jonathan Coxhead Dr Helen Griffin Dr Marzena Kurzawa-Akanbi et al.	Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains	2017
Emerita Professor Susan Lindsay Dr Yaobo Xu Dr Steven Lisgo Lauren Harkin Dr Gavin Clowry et al.	HDBR Expression: A Unique Resource for Global and Individual Gene Expression Studies during Early Human Brain Development	2016
Dr Jonathan Coxhead Dr Marzena Kurzawa-Akanbi Raf Hussain Dr Angela Pyle Professor Patrick Chinnery et al.	Somatic mtDNA variation is an important component of Parkinson's disease	2016
Dr Brendan Payne Kris Gardner Dr Jonathan Coxhead Professor Patrick Chinnery	Deep Resequencing of Mitochondrial DNA	2015
Dr Angela Pyle Dr Gavin Hudson Dr Ian Wilson Dr Jonathan Coxhead Tania Smertenko et al.	Extreme-Depth Re-sequencing of Mitochondrial DNA Finds No Evidence of Paternal Transmission in Humans	2015
Dr Charalampos Tzoulis Dr Jonathan Coxhead Dr Brendan Payne Professor Patrick Chinnery Professor Laurence Bindoff et al.	Molecular Pathogenesis of Polymerase Gamma-Related Neurodegeneration	2014
Dr Gerald Pfeffer Professor Grainne Gorman Dr Helen Griffin Dr Marzena Kurzawa-Akanbi Dr Ian Wilson et al.	Mutations in the SPG7 gene cause chronic progressive external ophthalmoplegia through disordered mitochondrial DNA maintenance	2014
Dr Maria Lastowska Hani Al-Afghani Haya AL-Balool Harsh SHETH Dr Jonathan Coxhead et al.	Identification of a neuronal transcription factor network involved in medulloblastoma development	2013
Smatanova Borras Dayne Bromley Philip Scully Dr Jonathan Coxhead Dr Ann Curtis et al.	'Noonan Spectrum Test' - comprehensive screening for RASopathies	2012
Dr Brendan Payne Dr Ian Wilson Dr Patrick Yu Wai Man Dr Jonathan Coxhead Professor David Deehan et al.	Universal heteroplasmy of human mitochondrial DNA	2012
Haya AL-Balool Dr Mark Wade Dr Jonathan Coxhead Professor Julie Irving Professor David Elliott et al.	Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant	2011
Dr Jonathan Coxhead Seamus Kelly Professor John Mathers	Differential antineoplastic effects of butyrate in cells with and without a functioning DNA mismatch repair	2010
Dr Jonathan Coxhead Seamus Kelly Professor Sir John Burn Professor John Mathers	Cell kinetics and gene expression changes in colorectal cancer patients given resistant starch: a randomised controlled trial	2009
Dr Mark Leaver Dr Patricia Dominguez Cuevas Dr Jonathan Coxhead Dr Richard Daniel Professor Jeff Errington FRS et al.	Life without a wall or division machine in Bacillus subtilis	2009
Dr Jonathan Coxhead Professor Sir John Burn Dr Ann Curtis	Early experiences in amplicon sequencing using the Roche GS-FLX massively parallel DNA sequencer and its application within a diagnostic laboratory	2008
Dr Jonathan Coxhead Seamus Kelly Professor John Mathers	Role of DNA-mismatch repair in anti-neoplastic effects of butyrate	2008
Professor John Mathers Dr Jonathan Coxhead Dr John Tyson	Nutrition and DNA repair - Potential molecular mechanisms of action	2007
Dr Jonathan Coxhead Seamus Kelly Professor John Mathers	Role of resistant starch in colorectal cancer prevention: A prospective randomised controlled trial	2007
Dr Jonathan Coxhead Wendy Bal Dr Liz Williams Professor John Mathers	Reactive oxygen species generation in mismatch repair-proficient and -deficient colorectal cancer cell lines exposed to butyrate	2006
Dr Jonathan Coxhead Dr Liz Williams Professor John Mathers	DNA mismatch repair status may influence anti-neoplastic effects of butyrate	2005
Dr Jonathan Coxhead Wendy Bal Dr Brian Shenton Dr Liz Williams Professor John Mathers et al.	Effect of butyrate on induction of aneuploidy in colorectal carcinoma cell lines	2005
Dr Liz Williams Dr Jonathan Coxhead Professor John Mathers	Anti-cancer effects of butyrate: Use of micro-array technology to investigate mechanisms	2003