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Browsing publications by Dr Simon Wilkinson.

Newcastle AuthorsTitleYearFull text
Dr Simon Wilkinson
Development of a Gaussian Process – feature selection model to characterise (poly)dimethylsiloxane (Silastic®) membrane permeation2020
Dr Simon Wilkinson
The influence of diffusion cell type and experimental temperature on machine learning models of skin permeability2020
Arathi Kizhedath
Dr Simon Wilkinson
Professor Jarka Glassey
Assessment of hepatotoxicity and dermal toxicity of butyl paraben and methyl paraben using HepG2 and HDFn in vitro models2019
Wi Phatvej
Dr Harish Datta
Dr Simon Wilkinson
Dr Elaine Mutch
Professor Ann Daly
et al.
Endocytosis and lack of cytotoxicity of alkyl–capped silicon quantum dots prepared from porous silicon2019
Dr Simon Wilkinson
Model fitting for small skin permeability data sets: Hyperparameter optimisation in Gaussian Process Regression2018
Dr Bernadette Carroll
Diego Manni
Dr Rhoda Stefanatos
Fiona Menzies
Dr Graham Smith
et al.
Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis2018
Dr Simon Wilkinson
Public perceptions of emergency decontamination: Effects of intervention type and responder management strategy during a focus group study2018
Arathi Kizhedath
Dr Simon Wilkinson
Professor Jarka Glassey
Applicability of predictive toxicology methods for monoclonal antibody therapeutics: status Quo and scope2017
Laura Hudson
Dr Khimara Naidoo
Dr Simon Wilkinson
Professor Mark Birch-Machin
Bad air gets under your skin2017
Dr Simon Wilkinson
Inter-laboratory skin distribution study of 4-n-butyl resorcinol: The importance of liquid chromatography/mass spectrometry (HPLC–MS/MS) bioanalytical validation2017
Dr Simon Wilkinson
Linear or non-linear models for percutaneous absorption?2015
Dr Simon Wilkinson
Predictive Methods in Percutaneous Absorption2015
Dr Simon Wilkinson
The application of machine learning to the modelling of percutaneous absorption: An overview and guide2015
Dr Simon Wilkinson
Xenobiotic metabolizing enzymes in human skin and SkinEthic reconstructed human skin models2015
Dr Simon Wilkinson
Ex vivo studies for the passive transdermal delivery of low-dose naltrexone from a cream; detection of naltrexone and its active metabolite, 6β-naltrexol, using a novel LC Q-ToF MS assay2014
Dr Simon Wilkinson
Analysis of finite dose dermal absorption data: Implications for dermal exposure assessment2014
Dr Simon Wilkinson
Comparison of xenobiotic metabolizing enzyme activities in ex vivo human skin and reconstructed human skin models from SkinEthic2014
Dr Simon Wilkinson
Effect of occlusion on the percutaneous absorption of aluminium from antiperspirant products2014
Professor Faith Williams
Varshini Ravi
Dr SarahJayne Boulton
Dr Elaine Mutch
Dr Christopher Jewell
et al.
Factors influencing expression and specificity of carboxylesterases in skin: Implications for local and systemic paraben ester toxicity2014
Mark Hewitt
Dr Simon Wilkinson
Feature Selection Modelling for Percutaneous Absorption across Synthetic Membranes2014
Craig Moore
Dr Simon Wilkinson
Professor Peter Blain
Dr Michael Dunn
Dr Gillian Aust
et al.
Percutaneous absorption and distribution of organophosphates (chlorpyrifos and dichlorvos) following dermal exposure and decontamination scenarios using in vitro human skin model2014
Dr Simon Wilkinson
Professor Peter Blain
Professor Faith Williams
Use of a human skin in vitro model to investigate the influence of 'every-day' clothing and skin surface decontamination on the percutaneous penetration of organophosphates2014
Dr Simon Wilkinson
The application of gaussian processes in the prediction of permeability across a polydimethlysiloxane membrane2013
Dr Simon Wilkinson
Mathematical modelling of percutaneous absorption2012
Dr Simon Wilkinson
Modelling of absorption across skin and silicone membranes using non-linear auto-regressive moving average with exogenous input (NARMAX) methods2012
Dr Simon Wilkinson
The application of discriminant analysis and Machine Learning methods as tools to identify and classify compounds with potential as transdermal enhancers2012
Dr Simon Wilkinson
The application of machine learning methods to identify and classify potential transdermal enhancers2012
Dr Simon Wilkinson
The application of non-linear auto-regressive moving average with exogenous input (NARMAX) to modelling the absorption across human skin2012
Dr Simon Wilkinson
The application and limitations of mathematical modelling in the prediction of permeability across mammalian skin and polydimethylsiloxane membranes2011
Dr Simon Wilkinson
Transepidermal water loss for probing full-thickness skin barrier function: Correlation with tritiated water flux, sensitivity to punctures and diverse surfactant exposures2009
Dr Simon Wilkinson
Professor Faith Williams
Cutaneous metabolism2008
Matthew Traynor
Dr Simon Wilkinson
Professor Faith Williams
Metabolism of butoxyethanol in excised human skin in vitro2008
Dr Simon Wilkinson
Professor Faith Williams
Analysis, interpretation, and extrapolation of dermal permeation data using diffusion-based mathematical models2007
Matthew Traynor
Dr Simon Wilkinson
Professor Faith Williams
Corrigendum to "The influence of water mixtures on the dermal absorption of glycol ethers" [Toxicol. Appl. Pharmacol. 218 (2007) 128-134] (DOI:10.1016/j.taap.2006.09.019)2007
Dr Simon Wilkinson
Professor Faith Williams
Cutaneous metabolism2007
Dr Gillian Aust
Dr Simon Wilkinson
Dr Michael Dunn
Professor Faith Williams
Influence of formulation on the dermal absorption of pesticide actives at spray dilution concentrations2007
Ria Wilkinson
Dr Christopher Jewell
Dr Simon Wilkinson
Professor Faith Williams
Professor Peter Blain
et al.
The effect of in vitro receptor media choice on the percutaneous absorption of methyl paraben2007
Matthew Traynor
Dr Simon Wilkinson
Professor Faith Williams
The influence of water mixtures on the dermal absorption of glycol ethers2007
Matthew Traynor
Dr Simon Wilkinson
Professor Faith Williams
The influence of water mixtures on the dermal absorption of glycol ethers (vol 218, pg 128, 2007)2007
Dr Simon Wilkinson
Dr Laura Greaves
Professor Faith Williams
Interactions of skin thickness and physicochemical properties of test compounds in percutaneous penetration studies2006
Dr Simon Wilkinson
Professor Faith Williams
Inter- and intralaboratory variation of in vitro diffusion cell measurements: An international multicenter study using quasi-standardized methods and materials2005
Dr Simon Wilkinson
Professor Faith Williams
The relationship between in vivo dermal penetration studies in humans and in vitro predictions using human skin2005
Dr Simon Wilkinson
Clair Roper
Professor Faith Williams
CEFIC Workshop on methods to determine permeation for human risk assessment2004
Matthew Traynor
Dr Simon Wilkinson
Professor Faith Williams
Effects of water on the absorption of two glycol ethers through human skin in vitro2004
Dr Simon Wilkinson
Professor Faith Williams
In vitro predictions of skin absorption of caffeine, testosterone, and benzoic acid: A multi-centre comparison study2004
Dr Simon Wilkinson
Professor Faith Williams
Percutaneous penetration of malathion and parathion: Dose and vehicle effects2004
Dr Simon Wilkinson
Professor Faith Williams
Percutaneous penetration of parathion in ethanol and xylene vehicles2004
Dr Simon Wilkinson
Professor Faith Williams
Effects of experimental conditions on absorption of glycol ethers through human skin in vitro2002
Dr Simon Wilkinson
Professor Faith Williams
Effects of experimental conditions on absorption of glycol ethers through human skin in vitro2002
Dr Laura Greaves
Dr Simon Wilkinson
Professor Faith Williams
Factors affecting percutaneous absorption of caffeine in vitro2002
Dr Simon Wilkinson
PLFA profiles of microbial communities in decomposing conifer litters subject to moisture stress2002
Dr Simon Wilkinson
Professor Faith Williams
Dermal absorption of pyridine and some methyl pyridines in vitro2001
Dr Simon Wilkinson
Effects of fungal inocula on the decomposition of lignin and structural polysaccharides in Pinus sylvestris litter2001
Dr Simon Wilkinson
Professor Faith Williams
In vitro dermal absorption of liquids2001
Dr Simon Wilkinson
Spatial patterns of soil microbial communities in a Norway spruce (Picea abies) plantation2001