Toggle Main Menu Toggle Search

Open Access padlockePrints

Browsing publications by Dr Linda Hogarth.

Newcastle AuthorsTitleYearFull text
Dr Nicola Wyatt
Dr Linda Hogarth
Dianne Turner
Dr Miranda Patterson
Dr David Jamieson
et al.
Circulating Biomarkers of Frailty Are Associated with a Poor Prognosis in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC)2016
Dr Alastair Greystoke
Dr Linda Hogarth
Dr Miranda Morton
Liam Bolt
Dianne Turner
et al.
The introduction of the Cancer Research UK Stratified Medicine Programme 2 (CRUK SMP2) in North East England; lessons learned and experience gained2016
Dr Linda Hogarth
Emeritus Professor Andy Hall
p21WAF1 modulates drug-induced apoptosis and cell cycle arrest in B-cell precursor acute lymphoblastic leukemia2015
Dr Nicola Cresti
Dr Linda Hogarth
Phase I expansion of S-222611, a reversible inhibitor of EGFR and HER2, in advanced solid tumors, including patients with brain metastases.2015
Dr Sally Coulthard
Dr Chris Redfern
Svante Vikingsson
Dr Malin Lindqvist Appell
Emeritus Professor Andy Hall
et al.
Increased Sensitivity to Thiopurines in Methylthioadenosine Phosphorylase-Deleted Cancers2011
Dr Linda Hogarth
Emeritus Professor Andy Hall
p53-independent Epigenetic Repression of the p21WAF1 Gene in T-cell Acute Lymphoblastic Leukemia2011
Dr Sally Coulthard
Dr Chris Redfern
Dr Linda Hogarth
Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers [abstract]2010
Dr Linda Hogarth
Dr Chris Redfern
Emeritus Professor Andy Hall
Dr Holly Anderson
Marian Case
et al.
The effect of thiopurine drugs on DNA methylation in relation to TPMT expression2008
Elizabeth Matheson
Dr Linda Hogarth
Marian Case
Professor Julie Irving
Emeritus Professor Andy Hall
et al.
DHFR and MSH3 co-amplification in childhood acute lymphoblastic leukaemia, in vitro and in vivo2007
Marian Case
Emeritus Professor Andy Hall
Dr Linda Hogarth
Amanda Jones
Design, synthesis and initial in vitro evaluation of novel prodrugs for the treatment of cystinosis2006
Professor Nick Reynolds
Dr Helen Anderson
Gordon Taylor
Emeritus Professor Andy Hall
Dr Linda Hogarth
et al.
Thioguanine nucleotide levels correlate with clinical response in atopic eczema patients treated with azathioprine2006
Dr Simon Meggitt
Professor Nick Reynolds
Dr Helen Anderson
Gordon Taylor
Emeritus Professor Andy Hall
et al.
Thioguanine nucleotides in patients with moderate-to-severe atopic eczema treated with azathioprine2006
Professor Julie Irving
Clare Bloodworth
Dr Nicholas Bown
Marian Case
Dr Linda Hogarth
et al.
Loss of heterozygosity in childhood acute lymphoblastic leukemia detected by genome-wide microarray single nucleotide polymorphism analysis2005
Dr Sally Coulthard
Dr Linda Hogarth
The thiopurines: An update2005
Emeritus Professor Andy Hall
Clare Bloodworth
Dr Linda Hogarth
Dr Nicholas Bown
Professor Julie Irving
et al.
Loss of heterozygosity in childhood acute lymphoblastic leukaemia detected by genome-wide microarray single nucleotide polymorphism analysis2004
Dr Sally Coulthard
Dr Linda Hogarth
Old drugs-current perspectives2004
Dr Sally Coulthard
Emeritus Professor Andy Hall
Dr Linda Hogarth
The clinical impact of thiopurine methyltransferase polymorphisms on thiopurine treatment2004
Clare Bloodworth
Dr Linda Hogarth
Emeritus Professor Andy Hall
Role of mismatch repair in determining sensitivity to the topoisomerase II poisons2003
Dr Linda Hogarth
Dr Sally Coulthard
Emeritus Professor Andy Hall
Lindi Skitt
The effect of thiopurine methyltransferase on the cytotoxic action of thiopurine drugs2003
Dr Sally Coulthard
Dr Linda Hogarth
Dr Margaret Little
Elizabeth Matheson
Dr Chris Redfern
et al.
The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs2002
Dr Linda Hogarth
Lynne Minto
Enhanced expression and activity of DNA polymerase β in human ovarian tumor cells: impact on sensitivity towards antitumor agents2001
Dr Linda Hogarth
Dr Margaret Little
Lynne Minto
Dr Chris Redfern
Emeritus Professor Andy Hall
et al.
High thiopurine methyltransferase expression confers different levels of resistance with 6-thioguanine compared to 6-mercaptopurine.2001
Dr Linda Hogarth
Dr Margaret Little
Lynne Minto
Dr Chris Redfern
Emeritus Professor Andy Hall
et al.
In vitro evidence for differences in 6-mercaptopurine versus 6-thioguanine metabolism depending on TPMT status2001
Dr Sally Coulthard
Dr Linda Hogarth
Lynne Minto
Dr Chris Redfern
Emeritus Professor Andy Hall
et al.
High thiopurine methyltransferase expression confers different levels of resistance with 6-thioguanine compared to 6-mercaptopurine2000
Dr Linda Hogarth
Elizabeth Matheson
Lynne Minto
Dr Margaret Little
Emeritus Professor Andy Hall
et al.
Measurement of resistance to thiopurine drugs in cells with defective mismatch repair2000
Dr Linda Hogarth
Emeritus Professor Andy Hall
Increased BAX expression is associated with an increased risk of relapse in childhood acute lymphocytic leukemia1999
Emeritus Professor Andy Hall
Dr Linda Hogarth
Sensitivity of testis tumour cells to chemotherapeutic drugs: Role of detoxifying pathways1996
Dr Linda Hogarth
Professor Andrew Pearson
Emeritus Professor Andy Hall
The effect of treatment with high dose melphalan, cisplatin or carboplatin on levels of glutathione in plasma, erythrocytes, mononuclear cells and urine1996
Emeritus Professor Andy Hall
Elizabeth Matheson
Dr Linda Hogarth
Purification of an alpha class glutathione S-transferase from melphalan-resistant Chinese hamster ovary cells and demonstration of its ability to catalyze melphalan-glutathione adduct formation1994
Dr Linda Hogarth
Dr Michael Reid
Professor Stephen Proctor
Dr Peter Hamilton
Emeritus Professor Andy Hall
et al.
Raised intracellular glutathione levels correlate with in vitro resistance to cytotoxic drugs in leukaemic cells from patients with acute lymphoblastic leukaemia1994
Dr Linda Hogarth
Emeritus Professor Andy Hall
Cytosolic glutathione (GSH) levels of leukemic blasts in relation to in vitro anthracycline resistance1993