Publications by Dr Christopher Bacon - ePrints

Browsing publications by Dr Christopher Bacon.

Newcastle Authors	Title	Year
Professor Gareth Veal Professor Steve Wedge Dr Christopher Bacon Professor Philip Sloan Dr Alastair Greystoke et al.	A phase I dose-escalation study of AZD3965, an oral monocarboxylate transporter 1 inhibitor, in patients with advanced cancer	2023
Dr Christopher Bacon Dr Simon Bomken	Improving outcomes of childhood and young adult non-Hodgkin lymphoma (NHL); twenty-five years of research and collaboration within the framework of the European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL)	2023
Dr Alex Blain Dr Christopher Bacon Professor Vikki Rand Professor Matthew Collin	Spatial and molecular profiling of the mononuclear phagocyte network in classic Hodgkin lymphoma	2023
Dr Ugo Offor Dr Andrew Filby Dr Milos Ognjanovic Dr Gareth Parry Abbas Khushnood et al.	Defining the systemic immune landscape in children at an increased risk of posttransplant lymphoproliferative disease: The immunology of thymectomy and childhood cardiac transplant (ITHACA) study.	2022
Dr Alex Newman Dr Masood Zaka Dr Peixun Zhou Dr Alex Blain Dr Amy Erhorn et al.	Genomic abnormalities of TP53 define distinct risk groups of paediatric B-cell non-Hodgkin lymphoma	2022
Dr Simon Bomken Dr Amir Enshaei Dr Ed Schwalbe Dr Aneta Mikulasova Dr Masood Zaka et al.	Molecular characterisation and clinical outcome of B-cell precursor acute lymphoblastic leukaemia with IG-MYC rearrangement	2022
Dr Christopher Bacon	Genomic landscape of Epstein–Barr virus-positive extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue	2021
Dr Christopher Bacon	Molecular features of non-anaplastic peripheral T-cell lymphoma in children and adolescents	2021
Dr Christopher Bacon Dr George Petrides Dr Nicola Leech Dr Fiona Jenkinson Professor Ruth Plummer et al.	A case of malignant hyperlactaemic acidosis appearing on treatment with the mono-carboxylase transporter 1 inhibitor AZD3965.	2020
Dr Christopher Bacon Joseph O'Donoghue	Commentary on: Breast Implant-Associated Bilateral B-Cell Lymphoma	2020
Dr Jarmila Spegarova Dr Karin Engelhardt Dr Helen Griffin Dr Aneta Mikulasova Dr Meghan Acres et al.	Germline TET2 loss-of-function causes childhood immunodeficiency and lymphoma	2020
Dr Ugo Offor Dr Sujith Samarasinghe Dr Kevin Windebank Dr Mary Slatter Professor Andrew Gennery et al.	HSCT provides effective treatment for lymphoproliferative disorders in children with primary immunodeficiency	2020
Dr Ugo Offor Dr Christopher Bacon Dr Jessica Roberts Jason Powell Dr Malcolm Brodlie et al.	Transplantation For Congenital Heart Disease Is Associated With An Increased Risk Of Epstein-Barr Virus-Related Post-Transplant Lymphoproliferative Disorder In Children	2020
Alex Newman Dr Masood Zaka Dr Peixun Zhou Dr Amy Erhorn Amy Barnard et al.	Biallelic Inactivation of TP53 is Associated with an Increased Risk of Relapse in Paediatric B-Cell Non-Hodgkin Lymphoma(B-NHL)	2019
Dr Mary Slatter Dr Leigh McDonald Dr Christopher Bacon Dr Joaquim Majo Professor Andrew Gennery et al.	Late relapse of primary hemophagocytic lymphohistiocytosis after hematopoietic stem cell transplantation: a consequence of low-level chimerism from a carrier donor?	2019
Dr Peixun Zhou Dr Alex Blain Alex Newman Dr Masood Zaka Dr Ugo Offor et al.	Sporadic and endemic Burkitt lymphoma have frequent FOXO1 mutations but distinct hotspots in the AKT recognition motif	2019
Dr Peixun Zhou Dr Amir Enshaei Alex Newman Dr Amy Erhorn Amy Barnard et al.	A genomic classification model enables risk stratification of paediatric endemic Burkitt lymphoma	2018
Dr Peixun Zhou Dr Amir Enshaei Alex Newman Dr Amy Erhorn Amy Barnard et al.	A Genomic Classification Model Enables Risk Stratification of Paediatric Endemic Burkitt Lymphona in Malawi	2018
Dr Ugo Offor Dr Christopher Bacon Professor Andrew Gennery Dr Simon Bomken	An increased risk of post-transplant lymphoproliferative disorder in children after cardiac transplantation for congenital heart disease	2018
Dr Christopher Bacon Dr Mario Abinun	Biallelic RIPK1 mutations in humans cause severe immunodeficiency, arthritis, and intestinal inflammation	2018
Alex Newman Dr Masood Zaka Dr Peixun Zhou Dr Amy Erhorn Dr Rachel Crossland et al.	Biallelic inactivation of TP53 is associated with an increased risk of relapse in paediatric B-cell non-Hodgkin lymphoma (B-NHL)	2018
Dr Ugo Offor Dr Christopher Bacon Professor Andrew Gennery Dr Simon Bomken	Cardiac transplantation for congenital heart disease is associated with an increased risk of post-transplant lymphoproliferative disorder (PTLD) in children: a single centre experience	2018
Dr Simon Bomken Dr Christopher Bacon Professor Andrew Gennery	Current Understanding and Future Research Priorities in Malignancy Associated With Inborn Errors of Immunity and DNA Repair Disorders: The Perspective of an Interdisciplinary Working Group	2018
Alex Newman Dr Peixun Zhou Dr Masood Zaka Professor Christine Harrison FRCPath FMedSci Dr Simon Bomken et al.	Genomic landscape of adult and paediatric B-cell Non-Hodgkin lymphoma	2018
Dr Masood Zaka Dr Rachel Crossland Amy Barnard Sara Wilkinson Dr Simon Bomken et al.	Integrated analysis of the genomic and microRNA landscapes identifies dysregulated pathways associated with relapsed paediatric B-cell Non-Hodgkin lymphoma	2018
Dr Peixun Zhou Alex Newman Filbert Adlar Casey Broadbent Dr Alison Blain et al.	Investigation of FOXO1 mutations in paediatric endemic and sporadic Burkitt lymphoma	2018
Dr Christopher Bacon Dr Mario Abinun Professor Andrew Cant	Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study	2017
Dr Paul Milne Dr Venetia Bigley Dr Christopher Bacon Dr Naomi McGovern Dr Simon Bomken et al.	Hematopoietic origin of Langerhans cell histiocytosis and Erdheim Chester disease in adults	2017
Dr Richard Noble Dr Natalie Bell Dr Helen Blair Huw Thomas Nicole Phillips et al.	Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and burkitt lymphoma	2017
Dr Christopher Bacon Professor Andrew Cant	Activated PI3-kinase Delta Syndrome (APDS): Genetics, Immunodeficiency, Diagnosis and Related Pathology	2016
Dr Jill Hunter Dr Jacqueline Butterworth Helene Sellier Huw Thomas Dr Christopher Bacon et al.	The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma	2016
Dr Mark Wade Dr Nicola Sunter Dr Sarah Fordham Anna Long Dino Mašić et al.	c-MYC is a radiosensitive locus in human breast cells	2015
Dr Julian Thomas Dr Christopher Bacon Professor Andrew Cant Professor Sophie Hambleton	A new case of Fas-associated death domain protein deficiency and update on treatment outcomes	2015
Dr Christopher Bacon Dr Mario Abinun Professor Andrew Cant	Activated PI3-Kinase Delta Syndrome: Clinical, Radiological And Laboratory Features Of A Large Cohort	2015
Dr Rachel Crossland Dr Kile Green Dr Christopher Bacon Dr Vikki Rand	Direct digital profiling of multiplexed mRNA expression from degraded formalin fixed paraffin embedded aggressive paediatric B-cell lymphoma tumour tissue	2015
Dr Peixun Zhou Alex Newman Dr Amy Erhorn Dr Christopher Bacon Professor Simon Bailey et al.	Investigation of prognostic markers in endemic Burkitt lymphoma	2015
Dr Paul Milne Professor Matthew Collin Dr Venetia Bigley Dr Christopher Bacon Dr Naomi McGovern et al.	Mapping the BRAFV600E Hematopoietic Clone of Adult Multi-System Langerhans Cell Histiocytosis	2015
Dr Christopher Carey Dr Rachel Crossland Dr Christopher Bacon Dr Vikki Rand	Molecular Classification of MYC-Driven B-Cell Lymphomas by Targeted Gene Expression Profiling of Fixed Biopsy Specimens	2015
Dr Michael Mather Hannah Hayhurst Dr Christopher Bacon Dr Theresa Cole Professor Andrew Gennery et al.	Mutation of TNFRSF13B in a child with 22q11 deletion syndrome associated with granulomatous lymphoproliferation	2015
Dr Natalie Bell Dr Helen Blair Lisa Price Dr Katrina Wood Professor Hermann Josef Vormoor et al.	Patient-derived xenograft and in vivo bioluminescent modelling of B-cell NHL	2015
Dr Britta Vormoor Henrike Knizia Michael Batey Dr Ian Wilson Dr Petra Dildey et al.	Development of a Preclinical Orthotopic Xenograft Model of Ewing Sarcoma and Other Human Malignant Bone Disease Using Advanced In Vivo Imaging	2014
Dr Natalie Bell Dr Helen Blair Professor Hermann Josef Vormoor Dr Christopher Bacon Dr Vikki Rand et al.	Development of in Vivo Models of Paediatric Burkitt Lymphoma Allowing Therapeutic Target Analysis and Drug Testing	2014
Dr Xiao Wang Dr Christopher Bacon Alison Long Sarah Pagan Professor Matthew Collin et al.	Factor XIIIa identifies macrophages and cells of mesenchymal origin in the human skin	2014
Dr Christopher Bacon	Gamma Heavy Chain Disease Lacks the MYD88 L265p Mutation Associated with Lymphoplasmacytic Lymphoma	2014
Dr Christopher Bacon	Gamma Heavy Chain Disease Lacks the MYD88 L265P Mutation Associated with Lymphoplasmacytic Lymphoma	2014
Dr Rachel Crossland Dr Tryfonia Mainou-Fowler Dr Michal Sieniawski Dr Christopher Bacon Dr Vikki Rand et al.	High BACH2 gene Expression Is an Indicator of Poor Prognosis in Adult Diffuse Large B-Cell Lymphoma Treated with R-CHOP	2014
Dr Lisa Turnbull Dr David Bourn Dr Christopher Bacon Dr Michael Wright Dr Mario Abinun et al.	Phenotypic Variations of Cartilage Hair Hypoplasia: Granulomatous Skin Inflammation and Severe T Cell Immunodeficiency as Initial Clinical Presentation in Otherwise Well Child with Short Stature	2014
Dr Christopher Bacon Professor Andrew Cant	The Clinical Manifestations, Management and Outcomes of Activated PI3K-Delta Syndrome (APDS) in UK and Ireland Cohort	2014
Dr Rachel Dickinson Paul Milne Dr Laura Jardine Dr Naomi McGovern Dr Sharon Cookson et al.	The evolution of cellular deficiency in GATA2 mutation	2014
Dr Christopher Bacon Sarah Wilkinson Dr Gavin Spickett Dr Helen Lucraft Professor Graham Jackson et al.	Epstein-Barr virus-independent diffuse large B-cell lymphoma in DNA ligase 4 deficiency	2013
Dr Maria Lastowska Hani Al-Afghani Haya AL-Balool Harsh SHETH Dr Jonathan Coxhead et al.	Identification of a neuronal transcription factor network involved in medulloblastoma development	2013
Dr Christopher Bacon	Indolent T-cell lymphoproliferative disease of the gastrointestinal tract	2013
Dr Simon Bomken Dr Lars Buechler Dr Klaus Rehe Dr Frida Ponthan Dr Alex Elder et al.	Lentiviral marking of patient-derived acute lymphoblastic leukaemic cells allows in vivo tracking of disease progression	2013
Dr Christopher Bacon	Gamma Heavy-chain Disease: Defining the Spectrum of Associated Lymphoproliferative Disorders Through Analysis of 13 Cases	2012
Dr Lisa Turnbull Dr David Bourn Dr Michael Wright Dr Christopher Bacon Dr Mario Abinun et al.	Granulomatous inflammation at presentation of severe T cell immunodeficiency due to RMRP mutation (cartilage-hair hypoplasis)	2012
Sarah Wilkinson Amy Bradburn Professor Simon Bailey Dr Christopher Bacon Dr Vikki Rand et al.	High-resolution genome-wide analysis of endemic Burkitt Lymphoma using DNA extracted from fine-needle aspirates preserved at ambient temperature	2012
Professor Sophie Hambleton Dr Venetia Bigley Professor Muzlifah Haniffa Dr Christopher Bacon Professor Andrew Cant et al.	IRF8 Mutations and Human Dendritic-Cell Immunodeficiency	2011
Dr Christopher Bacon	BIOMED-2 PCR assays for IGK gene rearrangements are essential for B-cell clonality analysis in follicular lymphoma	2011
Dr Christopher Bacon	Cyclin D1 positive diffuse large B-cell lymphoma is a post-germinal center-type lymphoma without alterations in the CCND1 gene locus	2011
Dr Christopher Bacon	Cytogenetically complex SEC31A-ALK fusions are recurrent in ALK-positive large B-cell lymphomas	2011
Dr Christopher Bacon	EBV-Positive Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue in the Post-Transplant Setting: A Distinct Type of Monomorphic Post-Transplant Lymphoproliferative Disorder?	2011
Dr Christopher Bacon	EBV-Positive Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue in the Post-Transplant Setting: A Distinct Type of Monomorphic Post-Transplant Lymphoproliferative Disorder?	2011
Dr Christopher Bacon	EBV-Positive Extranodal Marginal Zone Lymphoma of Mucosa-associated Lymphoid Tissue in the Posttransplant Setting: A Distinct Type of Posttransplant Lymphoproliferative Disorder?	2011
Dr Katherine Sturgess Dr Mary Slatter Dr Venetia Bigley Professor Muzlifah Haniffa Dr Xiao Wang et al.	Reduced Intensity Hematopoietic Stem Cell Transplant Rescues Immune Function and Corrects Pulmonary Alveolar Proteinosis in DCML Deficiency/GATA 2 Mutation	2011
Dr Christopher Bacon	Continual monitoring of intraepithelial lymphocyte immunophenotype and clonality is more important than snapshot analysis in the surveillance of refractory coeliac disease	2010
Henrike Knizia Michael Batey Gilberto de Almeida Dr Ross Maxwell Dr Petra Dildey et al.	Development of an orthotopic model for human malignant bone diseases in immunocompromised NOD.Cg-Prkdc^scidIl2rg^tmlwjl/szj (NSG) mice	2010
Dr Christopher Bacon	Extranodal lymphoma	2010
Dr Christopher Bacon	Primary effusion lymphoma: Genomic profiling revealed amplification of SELPLG and CORO1C encoding for proteins important for cell migration	2010
Professor James Allan Dr Nicola Sunter Dr Andrew Hall Dr Christopher Bacon Jonathan Pointon et al.	Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia	2010
Dr Christopher Bacon Dr Ki Pang Professor Andrew Cant Professor Sophie Hambleton	Whole-exome-sequencing-based discovery of human FADD deficiency	2010
Dr Christopher Bacon	A20 deletion is associated with copy number gain at the TNFA/B/C locus and occurs preferentially in translocation-negative MALT lymphoma of the ocular adnexa and salivary glands	2009
Dr Christopher Bacon	Genomic Profiling of Pediatric ALK-Positive Anaplastic Large Cell Lymphoma: A Children's Cancer and Leukaemia Group Study	2009
Yan Huang Dr Christopher Bacon	Immunophenotype and Clonality of Intraepithelial Lymphocytes: Continual Monitoring is More Important Than Snapshot Analysis in the Surveillance of Refractory Coeliac Disease	2009
Dr Christopher Bacon	Most primary adrenal lymphomas are diffuse large B-cell lymphomas with non-germinal center B-cell phenotype, BCL6 gene rearrangement and poor prognosis	2009
Dr Christopher Bacon	Primary follicular lymphoma of the thyroid gland	2009
Dr Christopher Bacon	The Lymphoma-associated Fusion Tyrosine Kinase ITK-SYK Requires Pleckstrin Homology Domain-mediated Membrane Localization for Activation and Cellular Transformation	2009
Dr Christopher Bacon	FOXP1 abnormalities in lymphoma: translocation breakpoint mapping reveals insights into deregulated transcriptional control	2008
Dr Christopher Bacon	Chromosomal translocations involving BCL6 in MALT lymphoma	2008
Dr Christopher Bacon	Cyclin D1 – positive diffuse large B cell lymphoma	2008
Dr Christopher Bacon	Mantle cell lymphoma with aberrant expression of CD10	2008
Dr Christopher Bacon	Peripheral T cell lymphoma with a follicular growth pattern: derivation from follicular helper T (TFH) cells and relationship to angioimmunoblastic T cell lymphoma	2008
Dr Christopher Bacon	Translocations Involving the Immunoglobulin Heavy Chain Gene Locus Predict Better Survival in Gastric Diffuse Large B-Cell Lymphoma	2008