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Browsing publications by Dr Nicholas Bown.

Newcastle AuthorsTitleYearFull text
Dr Laura Woodhouse
Clark Crawford
Dr Scott Marshall
Dr Nicholas Bown
Dr Elaine Willmore
et al.
Assessment and targeting of the MDM2-p53 network in CLL2015
Professor Tim Gray
Dr Nicholas Bown
Crisis Within Social Capital? The Negative Impact on Natural Resources of Tension Between Household and Community Social Capital in a Migrant Ladino Enclave on Utila2012
Sarah Nicholson
Dr Nicholas Bown
Professor Steven Clifford
A feasibility study of real-time central pathology review (CPR) and molecular diagnostics for medulloblastoma in the United Kingdom2011
Dr Nicholas Bown
Professor John Lunec
Professor Deborah Tweddle
A Multilocus Technique for Risk Evaluation of Patients with Neuroblastoma2011
Professor Anthony Moorman
Dr Lucy Chilton
Dr Jennifer Wilkinson
Hannah Ensor
Dr Nicholas Bown
et al.
A population-based cytogenetic study of adults with acute lymphoblastic leukemia2010
Dr Nicholas Bown
Professor Christine Harrison FRCPath FMedSci
Cytogenetics of long-term survivors of ETV6-RUNX1 fusion positive acute lymphoblastic leukemia2010
Sarah Nicholson
Dr Nicholas Bown
Professor Steven Clifford
Establishment of real-time centralised pathology review (CPR) and molecular diagnostics for medulloblastoma in the United Kingdom2010
Dr Fathi Azribi
Dr Nicholas Bown
Dr Petra Dildey
Stephen Clark
Professor Ruth Plummer
et al.
Extraosseous Pericardial Ewing's Sarcoma2010
Sarina Sulong
Professor Anthony Moorman
Professor Julie Irving
Marian Case
Professor Simon Bailey
et al.
A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups2009
Professor Steven Clifford
Dr Nicholas Bown
A feasibility study of real-time biological characterisation of medulloblastoma in the United Kingdom2009
Kate Wilson
Marian Case
Lynne Minto
Professor Simon Bailey
Dr Nicholas Bown
et al.
Flow minimal residue disease monitoring of candidate leukemic stem cells defined by the immunophenotype, CD34+CD38lowCD19+ in B-lineage childhoood acute lymphoblastic leukemia2009
Professor Andrew Gennery
Dr Nicholas Bown
Dr Terence Flood
Professor Andrew Cant
Dr Mario Abinun
et al.
Assessment of reduced intensity conditioning regimens for haematopoietic stem cell transplantation in primary immunodeficiency2008
Professor Roderick Skinner
Dr Mark Velangi
Dr Nicholas Bown
Donor lymphocyte infusions for post-transplant relapse of refractory anemia with excess blasts and monosomy 72008
Professor Anne Dickinson
Dr Nicholas Bown
Professor Andrew Cant
Dr Mario Abinun
Professor Andrew Gennery
et al.
Long-term immune reconstitution after anti-CD52-treated or anti-CD34-treated hematopoietic stem cell transplantation for severe T-lymphocyte immunodeficiency2008
Marian Case
Elizabeth Matheson
Lynne Minto
Dr Nicholas Bown
Professor Simon Bailey
et al.
Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia2008
Dr Michael Griffiths
Dr Nicholas Bown
Ploidy and karyotype complexity are powerful prognostic indicators in the Ewing's sarcoma family of tumors: A study by the United Kingdom cancer cytogenetics and the children's cancer and leukaemia group2008
Marian Case
Elizabeth Matheson
Lynne Minto
Professor Christine Harrison FRCPath FMedSci
Dr Nicholas Bown
et al.
Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting2008
Dr Nicholas Bown
Comparison of MLPA and interphase FISH in chronic lymphocytic leukaemia2007
Dr Jane Carr-Wilkinson
Dr Nicholas Bown
Marian Case
Emeritus Professor Andy Hall
Professor John Lunec
et al.
High-resolution analysis of allelic imbalance in neuroblastoma cell lines by single nucleotide polymorphism arrays2007
Daniel Routledge
Dr David Bourn
Dr Nicholas Bown
Mike Cole
Professor Andrew Gennery
et al.
Quantitative assessment of mixed chimerism in allogeneic stem cell transplant patients - A comparison of molecular genetic and cytogenetic approaches2007
Emeritus Professor Andy Hall
Sarina Sulong
Professor Christine Harrison FRCPath FMedSci
Lynne Minto
Dr Nicholas Bown
et al.
Assessment of aneuploidy in childhood acute lymphoblastic leukaemia using high density oligonucleotide arrays.2006
Dr Jackie Langdon
Dr Jayne Lamont
Dr Debbie Scott
Dr Nicholas Bown
Professor David Ellison
et al.
Combined genome-wide allelotyping and copy number analysis identify frequent genetic losses without copy number reduction in medulloblastoma2006
Sarina Sulong
Professor Julie Irving
Marian Case
Lynne Minto
Dr Nicholas Bown
et al.
Comprehensive analysis of p16(INK4a) in childhood acute lymphoblastic leukemia reveals homozygous deletion, haploinsufficiency and acquired isodisomy at the 9p locus with intact p16(INK4a).2006
Professor Julie Irving
Lynne Minto
Elizabeth Matheson
Marian Case
Professor Simon Bailey
et al.
Mutation in genes impacting on the RAS-RAF-MEK-ERK pathway are found at high incidence in childhood acute lymphoblastic leukemia at both diagnosis and at relapse.2006
Professor Anthony Moorman
Dr Nicholas Bown
Professor Christine Harrison FRCPath FMedSci
PAX5-ETV6 fusion in acute lymphoblastic leukaemia des not define the dic(9;12)2006
Dr Michael Griffiths
Dr Hazel Powell
Dr Ann Curtis
Dr Nicholas Bown
Acquired isodisomy for chromosome 13 is common and associated with FLT3-itd mutations in AML2005
Dr Ann Curtis
Dr Nicholas Bown
Acquired Isodisomy for chromosome 13 is common in AML, and associated with FLT3-itd mutations2005
Professor Julie Irving
Clare Bloodworth
Dr Nicholas Bown
Marian Case
Dr Linda Hogarth
et al.
Loss of heterozygosity in childhood acute lymphoblastic leukemia detected by genome-wide microarray single nucleotide polymorphism analysis2005
Dr Hazel Powell
Dr Ann Curtis
Dr Nicholas Bown
Dr Philip Taylor
No correlation between trisomy 13 and FLT3 duplication in acute myeloid leukemia2005
Dr Nicholas Bown
Dr David Bourn
Quantitative assessment of mixed chimerism in bone marrow transplant patients: a comparison of molecular genetic and cytogenetic approaches.2005
Dr Nicholas Bown
Dr Hazel Powell
Dr Ann Curtis
Incidence and clinical significance of FLT3 internal tandem duplications in acute myeloid leukaemia.2004
Emeritus Professor Andy Hall
Clare Bloodworth
Dr Linda Hogarth
Dr Nicholas Bown
Professor Julie Irving
et al.
Loss of heterozygosity in childhood acute lymphoblastic leukaemia detected by genome-wide microarray single nucleotide polymorphism analysis2004
Dr John Byrne
Julie Freeman-Edward
Gavin Cuthbert
Dr Nicholas Bown
Imatinib improves but may not fully reverse the poor prognosis of patients with CML with derivative chromosome 9 deletions2003
Professor Anthony Moorman
Dr Nicholas Bown
Dr Penelope Taylor
Professor Stephen Proctor
Population-based study of unselected acute myeloid leukemia cases reveals distinct cytogenetic pathways analogous to therapy-related AML/MDS2003
Dr Nicholas Bown
Julie Freeman-Edward
Professor John Lunec
Dr Katia Mazzocco
Steven O'Neill
et al.
Quality assessment of genetic markers used for therapy stratification2003
Dr Mark Velangi
Dr Michael Reid
Dr Nicholas Bown
Professor Graham Jackson
Professor Stephen Proctor
et al.
Acute lymphoblastic leukaemia of the L3 subtype in adults in the Northern health region of England 1983-992002
Dr Nicholas Bown
Simon Cotterill
Dr Michael Griffiths
Cytogenetic abnormalities and clinical outcome in Wilms tumor: A study by the UK Cancer Cytogenetics Group and the UK Children's Cancer Study Group2002
Dr Nicholas Bown
Diagnostic detection of AML1/ETO gene fusion by polymerase chain reaction2002
Dr Anne Lennard
Dr Nicholas Bown
Late-appearing MLL rearrangement arising as a secondary change in adult acute myeloid leukemia2002
Dr Seamus O'Neill
Dr Nicholas Bown
Comparative genomic hybridization in pineal parenchymal tumors2001
Dr Maria Lastowska
Simon Cotterill
Dr Nicholas Bown
Dr Katia Mazzocco
Professor Andrew Pearson
et al.
Comprehensive genetic and histopathologic study reveals three types of neuroblastoma tumors2001
Gavin Cuthbert
Julie Freeman-Edward
Dr Anne Lennard
Professor Stephen O'Brien
Dr Nicholas Bown
et al.
Der(9) deletions and response to STI571(Glivec (R)) treatment in chronic phase CML patients.2001
Professor Deborah Tweddle
Professor Archibald Malcolm
Dr Nicholas Bown
Professor Andrew Pearson
Professor John Lunec
et al.
Evidence for the development of p53 mutations after cytotoxic therapy in a neuroblastoma cell line2001
Dr Maria Lastowska
Dr Nicholas Bown
Professor John Lunec
Professor Tom Strachan
Professor Andrew Pearson
et al.
Molecular cytogenetic definition of 17q translocation breakpoints in neuroblastoma2001
Dr Maria Lastowska
Dr Nicholas Bown
Professor John Lunec
Professor Tom Strachan
Professor Andrew Pearson
et al.
Molecular cytogenetic definition of 17q translocation breakpoints in neuroblastoma2001
Gavin Cuthbert
Professor Christine Harrison FRCPath FMedSci
Dr Michael Griffiths
Dr Nicholas Bown
MLL amplification in acute leukaemia: a United Kingdom Cancer Cytogenetics Group (UKCCG) study2000
Simon Cotterill
Dr Nicholas Bown
Cytogenetically cryptic AML1 - ETO and CBFβ - MYH11 gene rearrangements: Incidence in 412 cases of acute myeloid leukaemia2000
Dr Nicholas Bown
Professor John Lunec
Professor Archibald Malcolm
Professor Andrew Pearson
Fluorescence in situ hybridization techniques for the rapid detection of genetic prognostic factors in neuroblastoma2000
Gavin Cuthbert
Karen Thompson
Dr Nicholas Bown
Sensitivity of FISH in detection of MLL traslocations2000
Dr Nicholas Bown
Simon Cotterill
Dr Maria Lastowska
Dr Seamus O'Neill
Professor Andrew Pearson
et al.
Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma1999
Dr Maria Lastowska
Dr Nicholas Bown
Professor John Lunec
Professor Tom Strachan
Professor Andrew Pearson
et al.
Molecular cytogenetic delineation of 17q translocation breakpoints in neuroblastoma cell lines1998
Simon Cotterill
Professor Andrew Pearson
Dr Nicholas Bown
Gain of chromosome arm 17q predicts unfavourable outcome in neuroblastoma patients1997
Dr Maria Lastowska
Professor Andrew Pearson
Dr John Wolstenholme
Dr Nicholas Bown
Promiscuous translocations of chromosome arm 17q in human neuroblastomas1997
Dr Nicholas Bown
Professor Archibald Malcolm
Dr Michael Reid
Professor Andrew Pearson
Solid alveolar rhabdomyosarcoma with a t(2;13)1995
Dr Nicholas Bown
Dr Michael Reid
Professor Archibald Malcolm
Emeritus Professor Alan Craft
Professor Andrew Pearson
et al.
Cytogenic abnormalities of small round-cell tumors1994
Dr Nicholas Bown
Dr Michael Reid
Professor Archibald Malcolm
Professor Andrew Pearson
Rapid detection of prognostic genetic factors in neuroblastoma using fluorescence in situ hybridisation on tumour imprints and bone marrow smears. United Kingdom Children's Cancer Study Group1994
Dr Penelope Taylor
Dr Michael Reid
Dr Nicholas Bown
Dr Peter Hamilton
Professor Stephen Proctor
et al.
Acute myeloid leukemia in the over 55s: A population-based study of incidence, treatment and outcome1993
Dr Nicholas Bown
Professor Andrew Pearson
Dr Michael Reid
High incidence of constitutional balanced translocations in neuroblastoma1993
Dr Michael Reid
Dr Peter Saunders
Dr Nicholas Bown
Emeritus Professor Alan Craft
Professor Archibald Malcolm
et al.
Alveolar rhabdomyosarcoma infiltrating bone marrow at presentation: the value to diagnosis of bone marrow trethine biopsy specimens1992
Dr Nicholas Bown
Professor Andrew Pearson
Dr Michael Reid
Cytogenetic studies of childhood solid tumors1989
Dr Nicholas Bown
Professor Andrew Pearson
Dr Michael Reid
Cytogenetic studies of pediatric solid tumors1989
Dr Nicholas Bown
Professor Andrew Pearson
Professor Archibald Malcolm
Cytogenetic abnormalities in a primitive neuroectodermal tumor1988
Professor Andrew Pearson
Dr Michael Reid
Dr Nicholas Bown
Professor Archibald Malcolm
Emeritus Professor Alan Craft
et al.
Cytogenetic investigations of solid tumours of children1988
Dr Nicholas Bown
Professor Andrew Pearson
Peter Crawford
Emeritus Professor Robert Perry
Multiple chromosome rearrangements in a childhood ependymoma1988
Dr Nicholas Bown
Dr Michael Reid
Professor Andrew Pearson
Professor Archibald Malcolm
Emeritus Professor Alan Craft
et al.
Cytogenic investigations in the assessment of response to treatment in neuroblastoma1987