Toggle Main Menu Toggle Search

Open Access padlockePrints

Browsing publications by Claire Schwab.

Newcastle AuthorsTitleYearFull text
Professor Anthony Moorman
Emilio Barretta
Ellie Butler
Eleanor Ward
Dr Amir Enshaei
et al.
Prognostic impact of chromosomal abnormalities and copy number alterations in adult B-cell precursor acute lymphoblastic leukaemia: a UKALL14 study2022
Claire Schwab
Professor Anthony Moorman
SSBP2-CSF1R is a recurrent fusion in B-lineage acute lymphoblastic leukemia with diverse genetic presentation and variable outcome2021
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study2021
Claire Schwab
Daniel Murdy
Ellie Butler
Dr Amir Enshaei
Emily Winterman
et al.
Genetic characterisation of childhood B-other-acute lymphoblastic leukaemia in UK patients by fluorescence in situ hybridisation and Multiplex Ligation-dependent Probe Amplification2021
Claire Schwab
MYB rearrangements and over-expression in T-cell acute lymphoblastic leukemia2021
Dr Tom Creasey
Dr Amir Enshaei
Claire Schwab
Kathryn Watts
Gavin Cuthbert
et al.
Single nucleotide polymorphism (SNP) array-based signature of low hypodiploidy in acute lymphoblastic leukemia2021
Dr Amir Enshaei
Professor Christine Harrison FRCPath FMedSci
Claire Schwab
Professor Anthony Moorman
A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia2020
Professor Anthony Moorman
Claire Schwab
Emily Winterman
Dr Frederik van Delft
Professor Christine Harrison FRCPath FMedSci
et al.
Adjuvant tyrosine kinase inhibitor therapy improves outcome for children and adolescents with acute lymphoblastic leukaemia who have an ABL-class fusion2020
Dr Matthew Bashton
Robin Hollis
Dr Sarra Ryan
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
et al.
Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia2020
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Design of a Comprehensive Fluorescence in Situ Hybridization Assay for Genetic Classification of T-Cell Acute Lymphoblastic Leukemia2020
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia2019
Dr Paul Sinclair
Dr Sarra Ryan
Dr Matthew Bashton
Shaun Hollern
Rebecca Hanna
et al.
SH2B3 inactivation through CN-LOH-12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain2019
Dr Tom Creasey
Dr Amir Enshaei
Kathryn Watts
Gavin Cuthbert
Claire Schwab
et al.
Single Nucleotide Polymorphism Array-Based Signature of Genetic Ploidy Groups in Acute Lymphoblastic Leukemia2019
Dr Lina Hamadeh
Dr Amir Enshaei
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
et al.
Validation of the United Kingdom copy-number alteration classifier in 3239 children with B-cell precursor ALL2019
Dr Paul Sinclair
Dr Helen Blair
Dr Sarra Ryan
Dr Lars Buechler
Joanna Cheng
et al.
Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 212018
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
The T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling2018
Dr Britta Vormoor
Professor Gareth Veal
Melanie Griffin
Professor Julie Irving
Lynne Minto
et al.
A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia2017
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Digital Multiplex Ligation-Dependent Probe Amplification for Detection of Key Copy Number Alterations in T- and B-Cell Lymphoblastic Leukemia2017
Dr Amir Enshaei
Professor Christine Harrison FRCPath FMedSci
Dr Sujith Samarasinghe
Claire Schwab
Professor Anthony Moorman
et al.
Genotype-Specific Minimal Residual Disease Interpretation Improves Stratification in Pediatric Acute Lymphoblastic Leukemia2017
Claire Schwab
Dr Lucy Chilton
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Intragenic amplification of PAX5: a novel subgroup in B-cell precursor acute lymphoblastic leukemia?2017
Professor Anthony Moorman
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Dr Sujith Samarasinghe
Use of minimal residual disease assessment to redefine induction failure in pediatric acute lymphoblastic leukemia2017
Claire Schwab
Sarra Ryan
Dr Lucy Chilton
Alannah Elliott
James Murray
et al.
EBF1-PDGFRB fusion in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL): genetic profile and clinical implications2016
Professor Anthony Moorman
Claire Schwab
Characterization of leukemias with ETV6-ABL1 fusion2016
Professor Christine Harrison FRCPath FMedSci
Claire Schwab
Constitutional abnormalities of chromosome 21 predispose to iAMP21-acute lymphoblastic leukaemia2016
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia2016
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Genetic characterization and therapeutic targeting of MYC translocated pediatric T-cell acute lymphoblastic leukemia2016
Professor Julie Irving
Dr Amir Enshaei
Dr Amy Erhorn
Lynne Minto
Claire Schwab
et al.
Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukaemia2016
Claire Schwab
Dr Amir Enshaei
Dr Lisa Russell
Professor Anthony Moorman
The Frequency and Outcome of Ph-like ALL Associated Abnormalities in Childhood Acute Lymphoblastic Leukaemia Treated on MRC UKALL20032016
Dr Sarra Ryan
Elizabeth Matheson
Dr Paul Sinclair
Dr Matthew Bashton
Claire Schwab
et al.
The role of the RAS pathway in iAMP21-ALL2016
Dr Al Gabriel
Dr Amir Enshaei
Jennifer Taylor
Dr Amy Erhorn
Claire Schwab
et al.
Age specific incidence of partner gene and secondary abnormalities in MLL positive acute lymphoblastic leukaemia (ALL)2015
Professor Anthony Moorman
Claire Schwab
Karen Marshall
Characterization of Leukemias with ETV6-ABL1 Fusion2015
Professor Anthony Moorman
Professor Julie Irving
Dr Amir Enshaei
Dr Amy Erhorn
Lynne Minto
et al.
Composite Index for Risk Prediction in Relapsed Childhood Acute Lymphoblastic Leukaemia2015
Dr Al Gabriel
Fadhel Alsaid Naji
Dr Ed Schwalbe
Dr Sirintra Nakjang
Dr Simon Cockell
et al.
Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia2015
Claire Schwab
Dr Amir Enshaei
Professor Anthony Moorman
Prognostic value of rare IKZF1 deletion in childhood b-cell precursor acute lymphoblastic leukemia: an international collaborative study2015
Dr Lindsay Nicholson
Elizabeth Matheson
Lynne Minto
Christopher Keilty
Maryna Sanichar
et al.
Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition2015
Dr Amir Enshaei
Claire Schwab
Dr Lucy Chilton
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
et al.
Risk Factor Analysis in Paediatric Acute Lymphoblastic Leukaemia with High Hyperdiploidy2015
Dr Amir Enshaei
Claire Schwab
Dr Lucy Chilton
Professor Anthony Moorman
Risk Factor Analysis in Paediatric Acute Lymphoblastic Leukaemia with High Hyperdiploidy2015
Claire Schwab
Alannah Elliott
Dr Lucy Chilton
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
et al.
Targeted Sequencing Identifies Association Between IL7R-JAK Mutations And Epigenetic Modulators In T-Cell Acute Lymphoblastic Leukemia.2015
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling2015
Claire Schwab
Dr Amir Enshaei
Professor Anthony Moorman
368 Prognostic Value of Rare IKZF1 deletions in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: An International Collaborative Study2014
Professor Anthony Moorman
Dr Amir Enshaei
Claire Schwab
Dr Lucy Chilton
Alannah Elliott
et al.
A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia2014
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
CMYC-translocations in t-cell acute lymphoblastic leukemia2014
Claire Schwab
Dr Sarra Ryan
Professor Christine Harrison FRCPath FMedSci
Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia2014
Claire Schwab
Becca Andrews
Dr Lucy Chilton
Alannah Elliott
Gerald Keil
et al.
EBF1-PDGFRB Fusion in Paediatric Acute Lymphoblastic Leukaemia (ALL): Genetic Profile and Clinical Implications2014
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Genetic profile of T-cell acute lymphoblastic leukemias with MYC translocations2014
Claire Schwab
Professor Anthony Moorman
Mouse xenograft modeling of human adult acute lymphoblastic leukemia provides mechanistic insights into adult LIC biology2014
Claire Schwab
Dr Amir Enshaei
Professor Anthony Moorman
Prognostic Value of Rare IKZF1 deletions in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: An International Collaborative Study2014
Professor Christine Harrison FRCPath FMedSci
Claire Schwab
Refinement of IKZF1 Genomic Status in Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia2014
Claire Schwab
Becca Andrews
Dr Lucy Chilton
Alannah Elliott
Dr Stacey Richardson
et al.
SSBP2-CSF1R Is a Recurrent Fusion in B-Other Acute Lymphoblastic Leukaemia with Variable Clinical Outcome2014
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
BTG1 deletions do not predict outcome in Down syndrome acute lymphoblastic leukemia2013
Dr Halima Al-shehhi
Claire Schwab
Dr Amy Erhorn
Dr Al Gabriel
Professor Christine Harrison FRCPath FMedSci
et al.
Abnormalities of the der(12)t(12;21) in ETV6-RUNX1 acute lymphoblastic leukemia2013
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Claire Schwab
Dr Lucy Chilton
An international study of intrachromosomal amplification of chromosome 21 (iAMP21): cytogenetic characterization and outcome2013
Claire Schwab
Dr Lucy Chilton
Heather Morrison
Lisa Jones
Dr Halima Al-shehhi
et al.
Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features2013
Professor Anthony Moorman
Dr Amir Enshaei
Claire Schwab
Dr Lucy Chilton
Integration Of Cytogenetic and Copy Number Alteration (CNA) Data Into a Single Risk Profile For Paediatric Acute Lymphoblastic Leukaemia (ALL)2013
Dr Amir Enshaei
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Long-term follow-up of ETV6-RUNX1 ALL reveals that NCI risk, rather than secondary genetic abnormalities, is the key risk factor2013
Professor Anthony Moorman
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Risk-Directed Treatment Intensification Significantly Reduces the Risk of Relapse Among Children and Adolescents With Acute Lymphoblastic Leukemia and Intrachromosomal Amplification of Chromosome 21: A Comparison of the MRC ALL97/99 and UKALL2003 Trials2013
Dr Emma Fairhall
Dr Michelle Charles
Karen Wallace
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
et al.
The B-13 hepatocyte progenitor cell resists pluripotency induction and differentiation to non-hepatocyte cells.2013
Dr Emma Fairhall
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Dr Karen Wallace
Professor Matthew Wright
et al.
The Hepatic Progenitor B-13 Cell Line Engrafts into the Mouse Liver and Transdifferentiates in Vivo2013
Dr Peter Carey
Claire Schwab
Dr Lucy Chilton
Dr Ed Schwalbe
Professor Roderick Skinner
et al.
Treating childhood acute lymphoblastic leukemia in Malawi2013
Professor Anthony Moorman
Claire Schwab
Hannah Ensor
Dr Lisa Russell
Heather Morrison
et al.
IGH@ Translocations, CRLF2 Deregulation and Microdeletions in Adolescents and Adults with Acute Lymphoblastic Leukemia2012
Claire Schwab
Dr Lucy Chilton
Dr Amir Enshaei
Heather Morrison
Lisa Jones
et al.
Clinical Relevance of Genes Commonly Deleted in Childhood B-Cell Precursor ALL (BCP-ALL)2012
Professor Anthony Moorman
Dr Amir Enshaei
Dr Lucy Chilton
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
et al.
Delineation of Risk Factors in Paediatric Acute Lymphoblastic Leukaemia with Favourable Cytogenetics2012
Claire Schwab
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Episomal amplification of NUP214-ABL1 fusion gene in B-cell acute lymphoblastic leukemia2012
Claire Schwab
Dr Lucy Chilton
Heather Morrison
Lisa Jones
Dr Halima Al-shehhi
et al.
Genes Commonly Deleted in Childhood B-Cell Precursor ALL (BCP-ALL) Are Associated with Major Cytogenetic Subgroups2012
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Claire Schwab
Intrachromosomal Amplification of Chromosome 21(iAMP21): Cytogenetic Characterisation and Outcome in Childhood B-Cell Precursor Acute Lymphoblastic Leukaemia (BCP-ALL). A Study On Behalf of the Ponte Di Legno International Childhood ALL Workshop2012
Dr Lisa Russell
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations2012
Hannah Ensor
Claire Schwab
Dr Lisa Russell
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
et al.
Treatment outcome of CRLF2-rearranged childhood acute lymphoblastic leukaemia: a comparative analysis of the AIEOP-BFM and UK NCRI-CCLG study groups2012
Hannah Ensor
Claire Schwab
Dr Lisa Russell
Heather Morrison
Dr Dino Masic
et al.
Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial2011
Dr Vikki Rand
Dr Lisa Russell
Claire Schwab
Hannah Ensor
Professor Julie Irving
et al.
Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia2011
Dr Lindsay Nicholson
Charlotte Evans
Elizabeth Matheson
Lynne Minto
Christopher Keilty
et al.
Quantitative Proteomic Analysis Reveals Maturation As a Mechanism Underlying Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia and PAX5 As a Re-Sensitising Therapeutic Target2011
Dr Sarra Ryan
Dr Vikki Rand
Claire Schwab
Heather Morrison
Elizabeth Matheson
et al.
Ras Signalling Pathway and Novel Target Genes Related to Down Syndrome Contribute to the Development of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) in iAMP21 Patients2011
Claire Schwab
Lisa Jones
Heather Morrison
Dr Sarra Ryan
Professor Christine Harrison FRCPath FMedSci
et al.
Evaluation of Multiplex Ligation-Dependent Probe Amplification as a Method for the Detection of Copy Number Abnormalities in B-Cell Precursor Acute Lymphoblastic Leukemia2010
Professor Christine Harrison FRCPath FMedSci
Claire Schwab
PHF6 mutations in T-cell acute lymphoblastic leukemia2010
Professor Anthony Moorman
Hannah Ensor
Dr Lucy Chilton
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
et al.
Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial2010
Dr Lisa Russell
Professor Olaf Heidenreich
Professor Julie Irving
Professor Anthony Moorman
Heather Morrison
et al.
Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia2009
Dr Vikki Rand
Dr Lisa Russell
Professor Julie Irving
Lisa Jones
Dr Dino Masic
et al.
What Is the Initiating Mechanism of iAMP21 in Childhood B Cell Precursor ALL?2009
Dr Carol English
Claire Schwab
Multiple structurally abnormal cell lines involving the same chromosome breakpoint: two cases detected by chorion villus biopsy2002