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Browsing publications by Dr Paul Sinclair

Newcastle AuthorsTitleYearFull text
Dr Paul Sinclair
Dr Ruth Cranston
Prahlad Raninga
Joanna Cheng
Rebecca Hanna
et al.		Disruption to the FOXO-PRDM1 axis resulting from deletions of chromosome 6 in acute lymphoblastic leukaemia2023
Sarra Ryan
Dr Ruth Cranston
Claire Schwab
Dr Matthew Bashton
Dr Paul Sinclair
et al.		The genomic landscape of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 212023
Dr Deepali Pal
Dr Helen Blair
Sean Hockney
Dr Melanie Beckett
Mankaran Singh
et al.		hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia2022
Emeritus Professor Amritpal Hungin
Dr Paul Sinclair
Knowledge gaps in the management of refractory reflux-like symptoms: Healthcare provider survey2022
Dr Paul Sinclair
Dr Sarra Ryan
Dr Matthew Bashton
Shaun Hollern
Rebecca Hanna
et al.		SH2B3 inactivation through CN-LOH-12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain2019
Dr Ruth Cranston
Dr Paul Sinclair
Dr Matthew Bashton
Dr Matthew Selby
Professor Christine Harrison
A Genome-Wide CRISPR Screen Implicates MYC Dysregulation in TCF3-PBX1 B-ALL2018
Dr Paul Sinclair
Dr Helen Blair
Dr Sarra Ryan
Dr Lars Buechler
Joanna Cheng
et al.		Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 212018
Zach Dixon
Dr Lindsay Nicholson
Elizabeth Matheson
Dr Paul Sinclair
Professor Christine Harrison
et al.		CREBBP knockdown enhances RAS/RAF/MEK/ERK signaling in Ras pathway mutated acute lymphoblastic leukemia but does not modulate chemotherapeutic response2017
Dr Alex Elder
Dr Klaus Rehe
Dr Simon Bomken
Dr Paul Sinclair
Katie Dormon
et al.		The ability to cross the blood-cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts.2016
Dr Sarra Ryan
Elizabeth Matheson
Dr Paul Sinclair
Dr Matthew Bashton
Claire Schwab
et al.		The role of the RAS pathway in iAMP21-ALL2016
Dr Paul Sinclair
Joanna Cheng
Prahlad Raninga
Rebecca Hanna
Shaun Hollern
et al.		A Targeted Functional Clone Tracking Assay for the Identification of Tumour Suppressor Genes in BCP- ALL Implicates the Transcription Factors FOXO3 and PRDM12015
Dr Klaus Rehe
Dr Simon Bomken
Dr Paul Sinclair
Dr Lisa Russell
Professor Olaf Heidenreich
et al.		Childhood pre-B acute lymphoblastic leukaemia cells capable of central nervous system engraftment are common, heterogeneous and transit the blood-cerebrospinal fluid barrier2015
Dr Jeyanthy Eswaran
Dr Paul Sinclair
Professor Olaf Heidenreich
Professor Julie Irving
Dr Lisa Russell
et al.		The pre-B-cell receptor checkpoint in acute lymphoblastic leukaemia2015
Claire Schwab
Sarra Ryan
Professor Anthony Moorman
Dr Richard McNally
Professor Bryan Young
et al.		Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia2014
Dr Jeyanthy Eswaran
Dr Paul Sinclair
Dr Sirintra Nakjang
Professor Christine Harrison
Identification of Cmtm Family Proteins As Tumor Suppressor and Membrane Regulator in B Cell Precursor Acute Lymphoblastic Leukemia2014
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