Publications by Gordon Taylor - ePrints

Browsing publications by Gordon Taylor.

Newcastle Authors	Title	Year
Dr Anthony Oxley Philip Berry Gordon Taylor Dr Joe Cowell Dr Michael Hall et al.	An LC/MS/MS method for stable isotope dilution studies of β-carotene bioavailability, bioconversion and vitamin A status in humans	2014
Dr Sally Coulthard Dr Chris Redfern Svante Vikingsson Dr Malin Lindqvist Appell Dr Andrew Hall et al.	Increased Sensitivity to Thiopurines in Methylthioadenosine Phosphorylase-Deleted Cancers	2011
Dr Simon Pridgeon Professor Rakesh Heer Gordon Taylor Professor Herbie Newell Kieran O'Toole et al.	Thiothymidine combined with UVA as a potential novel therapy for bladder cancer	2011
Huw Thomas Gordon Taylor Professor Herbie Newell Professor Alan Boddy	An evaluation of thymidine phosphorylase as a means of preventing thymidine rescue from the thymidylate synthase inhibitor raltitrexed	2007
Dr Jane Renwick Gordon Taylor Huw Thomas Professor Alan Boddy Dr Chris Redfern et al.	Molecular targeting of retinoic acid metabolism in neuroblastoma: The role of the CYP26 inhibitor R116010 in vitro and in vivo	2007
Professor Caroline Relton Gordon Taylor Professor Patrick Chinnery Emeritus Professor Doug Turnbull	Mitochondrial DNA mutations in individuals occupationally exposed to ionizing radiation	2006
Professor Nick Reynolds Dr Helen Anderson Gordon Taylor Dr Andrew Hall Dr Linda Hogarth et al.	Thioguanine nucleotide levels correlate with clinical response in atopic eczema patients treated with azathioprine	2006
Dr Simon Meggitt Professor Nick Reynolds Dr Helen Anderson Gordon Taylor Dr Andrew Hall et al.	Thioguanine nucleotides in patients with moderate-to-severe atopic eczema treated with azathioprine	2006
Professor Alan Boddy Gordon Taylor Dr Andrew Hughes Professor Alan Calvert Professor Herbie Newell et al.	2-[¹¹C]thymidine positron emission tomography as an indicator of thymidylate synthase inhibition in patients treated with AG337	2003
Huw Thomas Gordon Taylor Professor Herbie Newell Professor Alan Boddy	Potentiation of raltitrexed (RTX) in vitro by thymidine phosphorylase (TP) and TP distribution in vivo	2003
Huw Thomas Gordon Taylor Professor Herbie Newell Professor Alan Boddy	The in vivo distribution of a CEA directed antibody conjugated to thymidine phosphorylase	2002
Gordon Taylor Huw Thomas Professor Herbie Newell Professor Nicola Curtin	Hypoxanthine transport in human tumour cell lines. Relationship to the inhibition of hypoxanthine rescue by dipyridamole	2001
Professor Robert Taylor Gordon Taylor Dr Steve Durham Emeritus Professor Doug Turnbull	The determination of complete human mitochondrial DNA sequences in single cells: implications for the study of somatic mitochondrial DNA point mutations	2001
Gordon Taylor Professor Herbie Newell	Development of a whole cell assay to measure methotrexate-induced inhibition of thymidylate synthase and de novo purine synthesis in leukaemia cells	2000
Professor Alan Boddy Gordon Taylor	A phase I study of the lipophilic thymidylate synthase inhibitor Thymitaq® (nolatrexed dihydrochloride) given by 10-day oral administration	1999
Gordon Taylor Professor John Lunec Professor Andrew Pearson Professor Herbie Newell	Impact of polyglutamation on sensitivity to raltitrexed and methotrexate in relation to drug-induced inhibition of de novo thymidylate and purine biosynthesis in CCRF-CEM cell lines	1999
Gordon Taylor Professor Herbie Newell Professor Alan Boddy Andrew Johnston Professor Andrew Pearson et al.	Deoxyuridine plasma levels during the phase I study of nolatrexed in children with advanced cancer	1998
Professor Alan Boddy Gordon Taylor Professor Herbie Newell Professor Alan Calvert	Preclinical and phase I clinical studies with the nonclassical antifolate thymidylate synthase inhibitor nolatrexed dihydrochloride given prolonged administration in patients with solid tumors	1998
Professor Alan Calvert Dr Andrew Hall Professor John Lunec Professor Herbie Newell Professor Andrew Pearson et al.	The relationship between intrinsic thymidylate synthase expression and sensitivity to THYMITAQ® in human leukaemia and colorectal carcinoma cell lines	1997
Professor Steve Wedge Fiona Chapman Gordon Taylor Huw Thomas Professor Alan Boddy et al.	A phase I clinical study of the antipurine antifolate lometrexol (DDATHF) given with oral folic acid	1996
Gordon Taylor Professor Alan Boddy Professor Alan Calvert Andrew Johnston Professor Herbie Newell et al.	Clinical pharmacokinetic and pharmacodynamic studies with the nonclassical antifolate thymidylate synthase inhibitor 3,4-dihydro-2-amino-6-methyl-4-oxo-5-(4-pyridplthio)-quinazolone dihydrochloride (AG337) given by 24-hour continuous intravenous infusion	1995
Professor Steve Wedge Gordon Taylor Professor Alan Boddy Professor Alan Calvert Professor Herbie Newell et al.	Clinical pharmacokinetics of the antipurine antifolate (6R)-5,10-dideaza-5,6,7,8-tetrahydrofolic acid (lometrexol) administered with an oral folic acid supplement	1995
Professor Steve Wedge Gordon Taylor Professor Herbie Newell	Measurement of 5,10-dideaza-5,6,7,8-tetrahydrofolate (lometrexol) in human plasma and urine by high-performance liquid chromatography	1995
Professor Herbie Newell Gordon Taylor Professor Alan Calvert	Phase I and pharmacokinetic study of a water-soluble etoposide prodrug, etoposide phosphate (BMY-40481)	1995
Professor Herbie Newell Gordon Taylor Professor Alan Calvert	Thymidylate synthase - a target for anticancer drug design	1989
Professor Alan Calvert Gordon Taylor	Quinazoline antifolates with dual biochemical loci of action. Biochemical and Biological studies directed towards overcoming methotrexate resistance	1980
Professor Alan Calvert Gordon Taylor	The intracellular mechanism of action of metoprine (DDMP)	1980