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Browsing publications by
Dr Frida Ponthan.
Newcastle Authors
Title
Year
Full text
Dr Alex Elder
Dr Simon Bomken
Dr Ian Wilson
Dr Helen Blair
Dr Simon Cockell
et al.
Abundant and equipotent founder cells establish and maintain acute lymphoblastic leukaemia
2017
Judith Weiland
Dr Deepali Pal
Marian Case
Professor Julie Irving
Dr Frida Ponthan
et al.
BCP-ALL blasts are not dependent on CD19 expression for leukaemic maintenance
2016
Dr Frida Ponthan
Professor Olaf Heidenreich
Dr Kelly Coffey
Gene Silencing by RNAi in Mammalian Cells
2015
Professor Julie Irving
Elizabeth Matheson
Helen Blair
Marian Case
Isabella Swidenbank
et al.
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition.
Blood
. 2014;124(23):3420-3430
2015
Dr Frida Ponthan
Dr Simon Bomken
Dr Deepali Pal
Dr Alex Elder
Hesta McNeill
et al.
A Genome-Wide RNAi Screen to Identify Novel Genes Involved in Clonal Maintenance of ALL
2014
Dr Emma Bell
Dr Frida Ponthan
Claire Whitworth
Professor Deborah Tweddle
Professor John Lunec
et al.
COX2 expression in neuroblastoma increases tumorigenicity but does not affect cell death in response to the COX2 inhibitor celecoxib
2014
Professor Julie Irving
Elizabeth Matheson
Dr Helen Blair
Marian Case
Isabella Swidenbank
et al.
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition
2014
Michael Batey
Dr Frida Ponthan
Dr Helen Blair
Professor Olaf Heidenreich
The development and evaluation of a series of novel in vivo imaging models of AML for the assessment of drug efficacy
2014
Dr Frida Ponthan
Claire Whitworth
Huw Thomas
Dr Chris Redfern
Cell Survival Signalling through PPARĪ“ and Arachidonic Acid Metabolites in Neuroblastoma
2013
Dr Simon Bomken
Dr Lars Buechler
Dr Klaus Rehe
Dr Frida Ponthan
Dr Alex Elder
et al.
Lentiviral marking of patient-derived acute lymphoblastic leukaemic cells allows
in vivo
tracking of disease progression
2013
Michael Batey
Dr Frida Ponthan
Professor Olaf Heidenreich
The use of a novel
in vivo
orthotopic imaging model of AML for assessment of drug efficacy
2013
Dr Simon Bomken
Dr Lars Buechler
Dr Klaus Rehe
Dr Frida Ponthan
Dr Helen Blair
et al.
Lentiviral Transduction of Patient Derived Leukaemic Blasts Allowing In Vivo Bioluminescent Monitoring in An NSG Model of Leukaemia Stem Cell Maintenance
2011
Dr Frida Ponthan
Hesta McNeill
Dr Lars Buechler
Professor Hermann Josef Vormoor
Professor Olaf Heidenreich
et al.
Significance of Fusion Genes for Maintenance of Leukaemia
2011
Dr Frida Ponthan
Professor Olaf Heidenreich
A
Drosophila
model identifies calpains as modulators of the human leukemogenic fusion protein AML1-ETO
2009
Dr Frida Ponthan
Expression of enzymes and receptors of the leukotriene pathway in human neuroblastoma promotes tumor survival and provides a target for therapy
2008
Dr Katrina Wood
Dr Michael Jackson
Dr Maria Lastowska
Dr Darroch Hall
Dr Helen Imrie
et al.
Histological profile of tumours from MYCN transgenic mice
2008
Dr Frida Ponthan
Dr Chris Redfern
Celecoxib prevents neuroblastoma tumor development and potentiates the effect of chemotherapeutic drugs in vitro and in vivo
2007
Dr Frida Ponthan
Neuroblastoma cell death in response to docosahexaenoic acid: Sensitization to chemotherapy and arsenic-induced oxidative stress
2006
Dr Frida Ponthan
The antimicrobial peptide, lactoferricin B, is cytotoxic to neuroblastoma cells
in vitro
and inhibits xenograft growth
in vivo
2006
Dr Frida Ponthan
NSAIDs in neuroblastoma therapy
2005
Dr Frida Ponthan
Proton magnetic resonance spectroscopy in neuroblastoma: Current status, prospects and limitations
2005
Dr Frida Ponthan
Cyclooxygenase-2 is expressed in neuroblastoma, and nonsteroidal anti-inflammatory drugs induce apoptosis and inhibit tumor growth
in vivo
2004
Dr Frida Ponthan
Synergistic induction of apoptosis in neuroblastoma cells using a combination of cytostatic drugs with interferon-gamma and TRAIL
2004
Dr Frida Ponthan
Apoptosis and tumor remission in liver tumor xenografts by 4-phenylbutyrate
2003
Dr Frida Ponthan
Evaluation of anti-tumour effects of oral fenretinide (4-HPR) in rats with human neuroblastoma xenografts
2003
Dr Frida Ponthan
Noninvasive estimation of tumour viability in a xenograft model of human neuroblastoma with proton magnetic resonance spectroscopy (1H MRS)
2003
Dr Frida Ponthan
Quantitative analysis of tyrosine hydroxylase mRNA for sensitive detection of neuroblastoma cells in blood and bone marrow
2003
Dr Frida Ponthan
The synthetic retinoid RO 13-6307 induces neuroblastoma differentiation
in vitro
and inhibits neuroblastoma tumour growth
in vivo
2003
Dr Frida Ponthan
Bioavailability and dose-dependent anti-tumour effects of 9-
cis
retinoic acid on human neuroblastoma xenografts in rat
2001
Dr Frida Ponthan
Dr Chris Redfern
The vitamin A analogues: 13-
cis
retinoic acid, 9-
cis
retinoic acid, and Ro 13-6307 inhibit neuroblastoma tumour growth in vivo
2001
Dr Frida Ponthan
Human polyomavirus BK (BKV) and neuroblastoma: Mechanisms of oncogenic action and possible strategy for novel treatment
2000