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Browsing publications by Dr Frida Ponthan.

Newcastle AuthorsTitleYearFull text
Dr Alex Elder
Dr Simon Bomken
Dr Ian Wilson
Dr Helen Blair
Dr Simon Cockell
et al.
Abundant and equipotent founder cells establish and maintain acute lymphoblastic leukaemia2017
Judith Weiland
Dr Deepali Pal
Marian Case
Professor Julie Irving
Dr Frida Ponthan
et al.
BCP-ALL blasts are not dependent on CD19 expression for leukaemic maintenance2016
Dr Frida Ponthan
Professor Olaf Heidenreich
Dr Kelly Coffey
Gene Silencing by RNAi in Mammalian Cells2015
Professor Julie Irving
Elizabeth Matheson
Helen Blair
Marian Case
Isabella Swidenbank
et al.
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition. Blood. 2014;124(23):3420-34302015
Dr Frida Ponthan
Dr Simon Bomken
Dr Deepali Pal
Dr Alex Elder
Hesta McNeill
et al.
A Genome-Wide RNAi Screen to Identify Novel Genes Involved in Clonal Maintenance of ALL2014
Dr Emma Bell
Dr Frida Ponthan
Claire Whitworth
Professor Deborah Tweddle
Professor John Lunec
et al.
COX2 expression in neuroblastoma increases tumorigenicity but does not affect cell death in response to the COX2 inhibitor celecoxib2014
Professor Julie Irving
Elizabeth Matheson
Dr Helen Blair
Marian Case
Isabella Swidenbank
et al.
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition2014
Michael Batey
Dr Frida Ponthan
Dr Helen Blair
Professor Olaf Heidenreich
The development and evaluation of a series of novel in vivo imaging models of AML for the assessment of drug efficacy2014
Dr Frida Ponthan
Claire Whitworth
Huw Thomas
Dr Chris Redfern
Cell Survival Signalling through PPARĪ“ and Arachidonic Acid Metabolites in Neuroblastoma2013
Dr Simon Bomken
Dr Lars Buechler
Dr Klaus Rehe
Dr Frida Ponthan
Dr Alex Elder
et al.
Lentiviral marking of patient-derived acute lymphoblastic leukaemic cells allows in vivo tracking of disease progression2013
Michael Batey
Dr Frida Ponthan
Professor Olaf Heidenreich
The use of a novel in vivo orthotopic imaging model of AML for assessment of drug efficacy2013
Dr Simon Bomken
Dr Lars Buechler
Dr Klaus Rehe
Dr Frida Ponthan
Dr Helen Blair
et al.
Lentiviral Transduction of Patient Derived Leukaemic Blasts Allowing In Vivo Bioluminescent Monitoring in An NSG Model of Leukaemia Stem Cell Maintenance2011
Dr Frida Ponthan
Hesta McNeill
Dr Lars Buechler
Professor Hermann Josef Vormoor
Professor Olaf Heidenreich
et al.
Significance of Fusion Genes for Maintenance of Leukaemia2011
Dr Frida Ponthan
Professor Olaf Heidenreich
A Drosophila model identifies calpains as modulators of the human leukemogenic fusion protein AML1-ETO2009
Dr Frida Ponthan
Expression of enzymes and receptors of the leukotriene pathway in human neuroblastoma promotes tumor survival and provides a target for therapy2008
Dr Katrina Wood
Dr Michael Jackson
Dr Maria Lastowska
Dr Darroch Hall
Dr Helen Imrie
et al.
Histological profile of tumours from MYCN transgenic mice2008
Dr Frida Ponthan
Dr Chris Redfern
Celecoxib prevents neuroblastoma tumor development and potentiates the effect of chemotherapeutic drugs in vitro and in vivo2007
Dr Frida Ponthan
Neuroblastoma cell death in response to docosahexaenoic acid: Sensitization to chemotherapy and arsenic-induced oxidative stress2006
Dr Frida Ponthan
The antimicrobial peptide, lactoferricin B, is cytotoxic to neuroblastoma cells in vitro and inhibits xenograft growth in vivo2006
Dr Frida Ponthan
NSAIDs in neuroblastoma therapy2005
Dr Frida Ponthan
Proton magnetic resonance spectroscopy in neuroblastoma: Current status, prospects and limitations2005
Dr Frida Ponthan
Cyclooxygenase-2 is expressed in neuroblastoma, and nonsteroidal anti-inflammatory drugs induce apoptosis and inhibit tumor growth in vivo2004
Dr Frida Ponthan
Synergistic induction of apoptosis in neuroblastoma cells using a combination of cytostatic drugs with interferon-gamma and TRAIL2004
Dr Frida Ponthan
Apoptosis and tumor remission in liver tumor xenografts by 4-phenylbutyrate2003
Dr Frida Ponthan
Evaluation of anti-tumour effects of oral fenretinide (4-HPR) in rats with human neuroblastoma xenografts2003
Dr Frida Ponthan
Noninvasive estimation of tumour viability in a xenograft model of human neuroblastoma with proton magnetic resonance spectroscopy (1H MRS)2003
Dr Frida Ponthan
Quantitative analysis of tyrosine hydroxylase mRNA for sensitive detection of neuroblastoma cells in blood and bone marrow2003
Dr Frida Ponthan
The synthetic retinoid RO 13-6307 induces neuroblastoma differentiation in vitro and inhibits neuroblastoma tumour growth in vivo2003
Dr Frida Ponthan
Bioavailability and dose-dependent anti-tumour effects of 9-cis retinoic acid on human neuroblastoma xenografts in rat2001
Dr Frida Ponthan
Dr Chris Redfern
The vitamin A analogues: 13-cis retinoic acid, 9-cis retinoic acid, and Ro 13-6307 inhibit neuroblastoma tumour growth in vivo2001
Dr Frida Ponthan
Human polyomavirus BK (BKV) and neuroblastoma: Mechanisms of oncogenic action and possible strategy for novel treatment2000