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Browsing publications by Dr Sarra Ryan.

Newcastle AuthorsTitleYearFull text
Dr Tom Creasey
Emilio Barretta
Dr Sarra Ryan
Ellie Butler
Dr Daniel Leongamornlert
et al.
Genetic and genomic analysis of acute lymphoblastic leukaemia in older adults reveals a distinct profile of abnormalities: analysis of 210 patients from the UKALL14 and UKALL60+ clinical trials2021
Claire Schwab
Daniel Murdy
Ellie Butler
Dr Amir Enshaei
Emily Winterman
et al.
Genetic characterisation of childhood B-other-acute lymphoblastic leukaemia in UK patients by fluorescence in situ hybridisation and Multiplex Ligation-dependent Probe Amplification2021
Dr Matthew Bashton
Robin Hollis
Dr Sarra Ryan
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
et al.
Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia2020
Dr Paul Sinclair
Dr Sarra Ryan
Dr Matthew Bashton
Shaun Hollern
Rebecca Hanna
et al.
SH2B3 inactivation through CN-LOH-12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain2019
Dr Paul Sinclair
Dr Helen Blair
Dr Sarra Ryan
Dr Lars Buechler
Joanna Cheng
et al.
Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 212018
Dr Janet Lindsey
Dr Rebecca Hill
Dr Ed Schwalbe
Dr Christopher Howell
Dr Reza Rafiee
et al.
Molecular and Prognostic Heterogeneity within MYC and MYCN Amplified Medulloblastomas2016
Dr Sarra Ryan
Elizabeth Matheson
Dr Paul Sinclair
Dr Matthew Bashton
Claire Schwab
et al.
The role of the RAS pathway in iAMP21-ALL2016
Dr Paul Sinclair
Joanna Cheng
Prahlad Raninga
Rebecca Hanna
Shaun Hollern
et al.
A Targeted Functional Clone Tracking Assay for the Identification of Tumour Suppressor Genes in BCP- ALL Implicates the Transcription Factors FOXO3 and PRDM12015
Dr Lisa Russell
Lisa Jones
Dr Amir Enshaei
Jamie Rutherford
Dr Stefano Tonin
et al.
Clincial and Genetic Landscapes Differ Between IGH-CRLF2 and P2RY8-CRLF2 Acute Lymphoblastic Leukaemia2015
Dr Lisa Russell
Lisa Jones
Dr Amir Enshaei
Dr Stefano Tonin
Dr Sarra Ryan
et al.
Clincial and Genetic Landscapes Differ Between IGH-CRLF2 and P2RY8-CRLF2 Acute Lymphoblastic Leukaemia2015
Claire Schwab
Dr Sarra Ryan
Professor Christine Harrison FRCPath FMedSci
Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia2014
Claire Schwab
Becca Andrews
Dr Lucy Chilton
Alannah Elliott
Gerald Keil
et al.
EBF1-PDGFRB Fusion in Paediatric Acute Lymphoblastic Leukaemia (ALL): Genetic Profile and Clinical Implications2014
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Daniel Williamson
Dr Sarra Ryan
et al.
MYC and TP53 defects emerge and interact at medulloblastoma relapse, define rapidly progressive disease and can be targeted therapeutically2014
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Karen Barker
Dr Daniel Williamson
et al.
MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically2014
Jake Clayton
Joanna Cheng
Dr Sarra Ryan
Professor Christine Harrison FRCPath FMedSci
Dr Paul Sinclair
et al.
Oncogenomic Screening Strategies to Identify Tumour Suppressor Genes on Chromosome 12 in Acute Myeloid Leukaemia2014
Claire Schwab
Becca Andrews
Dr Lucy Chilton
Alannah Elliott
Dr Stacey Richardson
et al.
SSBP2-CSF1R Is a Recurrent Fusion in B-Other Acute Lymphoblastic Leukaemia with Variable Clinical Outcome2014
Dr Sarra Ryan
Dr Ed Schwalbe
Mike Cole
Yuan Lu
Dr Meryl Lusher
et al.
MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma2012
Professor David Ellison
Dr Hisham Megahed
Dr Meryl Lusher
Dr Sarra Ryan
Professor Simon Bailey
et al.
Definition of Disease-Risk Stratification Groups in Childhood Medulloblastoma Using Combined Clinical, Pathologic, and Molecular Variables2011
Dr Vikki Rand
Dr Lisa Russell
Claire Schwab
Hannah Ensor
Professor Julie Irving
et al.
Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia2011
Dr Ed Schwalbe
Dr Janet Lindsey
Debbie Straughton
Mike Cole
Dr Hisham Megahed
et al.
Rapid Diagnosis of Medulloblastoma Molecular Subgroups2011
Dr Sarra Ryan
Dr Vikki Rand
Claire Schwab
Heather Morrison
Elizabeth Matheson
et al.
Ras Signalling Pathway and Novel Target Genes Related to Down Syndrome Contribute to the Development of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) in iAMP21 Patients2011
Dr Hisham Megahed
Dr Sarra Ryan
Dr Meryl Lusher
Sarah Nicholson
Professor Simon Bailey
et al.
Clinical, Pathological, and Molecular Variables Define Risk-Stratification Groups in Childhood Medulloblastoma2010
Professor David Ellison
Dr Hisham Megahed
Dr Sarra Ryan
Dr Meryl Lusher
Sarah Nicholson
et al.
Clinical, pathological, and molecular variables define risk-stratification groups in childhood medulloblastoma2010
Claire Schwab
Lisa Jones
Heather Morrison
Dr Sarra Ryan
Professor Christine Harrison FRCPath FMedSci
et al.
Evaluation of Multiplex Ligation-Dependent Probe Amplification as a Method for the Detection of Copy Number Abnormalities in B-Cell Precursor Acute Lymphoblastic Leukemia2010
Dr James Hayden
Dr Matthew Allen
Dr Sarra Ryan
Sarah Nicholson
Dr Ed Schwalbe
et al.
Molecular Mechanisms in Supratentorial CNS-PNET development2010
Professor Steven Clifford
Dr Sarra Ryan
Mike Cole
Dr Meryl Lusher
Kieran O'Toole
et al.
MYC gene family amplification and expression in childhood medulloblastoma: Biological significance and utility for high-risk disease stratification2010
Dr Sarra Ryan
Professor David Elliott
Professor David Ellison
Professor Simon Bailey
Professor Steven Clifford
et al.
Amplification and overexpression of Hsa-miR-3ob, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in medulloblastoma2009