Publications by Dr Fiona LeBeau - ePrints

Browsing publications by Dr Fiona LeBeau.

Newcastle Authors	Title	Year
Dr David Koss Dr Pawel Palmowski Dr Andrew Porter Dr Lauren Walker Professor Johannes Attems et al.	A reciprocal relationship between markers of genomic DNA damage and alpha-synuclein pathology in dementia with Lewy bodies	2025
Dr Fiona LeBeau	Age-dependent reduction in voltage-gated inward sodium current and Scn8a gene expression in murine stellate ganglia	2025
Dr Fiona LeBeau	Intact microdissection of stellate ganglia in a Parkinson's disease model reveals aggregation of mutant human α-synuclein in their cell bodies	2025
Dr Faye McLeod Dr Elaine Mcdermott Shermin Mak Dr Darren Walsh Mark Turnbull et al.	AAV8 vector induced gliosis following neuronal transgene expression.	2024
Dr Elizaveta Olkhova Dr Laura Alexandra Smith Dr Bethany Dennis Dr Yi Ng Dr Fiona LeBeau et al.	Delineating mechanisms underlying parvalbumin neuron impairment in different neurological and neurodegenerative disorders: the emerging role of mitochondrial dysfunction	2024
Ibtisam Al-Musawi Dr Bethany Dennis Dr Gavin Clowry Dr Fiona LeBeau	Evidence of prodromal changes in neuronal excitability and neuroinflammation in the hippocampus in young alpha-synuclein (A30P) transgenic mice	2024
Ashan Jayasekera Dr Jehill Parikh Professor Andrew Blamire Dr Fiona LeBeau Christopher Cowie et al.	Glutamate in glioma-related seizures	2024
Lucy Gee Amy Collins Lee Reed Dr Lee Borthwick Dr Christopher Morris et al.	Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ	2024
Dr Tamara Modebadze Ashan Jayasekera Christopher Cowie Dr Fiona LeBeau	Phylogenetic divergence of GABA_B receptor signalling in neocortical networks over adult life	2024
Dr Elizaveta Olkhova Carla Bradshaw Emeritus Professor Doug Turnbull Dr Fiona LeBeau Dr Yi Ng et al.	A novel mouse model of mitochondrial disease exhibits juvenile-onset severe neurological impairment due to parvalbumin cell mitochondrial dysfunction	2023
Lucy Gee Dr Ben Barron-Millar Dr Marco Zaki Dr Saimir Luli Rachel Burgoyne et al.	Anti–Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct–Ligated Mice	2023
Dr Fiona LeBeau	Clinical and Non-Clinical Cardiovascular Disease Associated Pathologies in Parkinson's Disease	2023
Dr Boubker Zaaimi Mark Turnbull Dr Anupam Hazra Professor Yujiang Wang Dr Carolina Gandara De Souza et al.	Closed-loop optogenetic control of normal and pathological network dynamics	2023
Dr Boubker Zaaimi Mark Turnbull Dr Anupam Hazra Professor Yujiang Wang Dr Carolina Gandara de Souza et al.	Closed-loop optogenetic control of the dynamics of neural activity in non-human primates	2023
Maznah Alhesain Hannah Ronan Dr Fiona LeBeau Dr Gavin Clowry	Expression of the schizophrenia associated gene FEZ1 in the early developing fetal human forebrain	2023
Dr Bethany Dennis Dr Stuart Neale Dr Fiona LeBeau Professor Tom Salt	Modulation of circuit oscillations in the rat anterior cingulate cortex (ACC) in vitro by mGlu2 metabotropic glutamate receptors and alleviation of the effects of phencyclidine-induced NMDA-receptor hypofunction	2023
Dimitrios Firfilionis Frances Hutchings Dr Reza Tamadoni Jahromi Dr Darren Walsh Mark Turnbull et al.	A Closed-Loop Optogenetic Platform	2021
Dr Clare Tweedy Nathan Kindred Professor John-Paul Taylor Dr Daniel Erskine Dr Christopher Morris et al.	Hippocampal network hyperexcitability in young transgenic mice expressing human mutant alpha-synuclein	2021
Dan Hayman Dr Tamara Modebadze Sarah Charlton Kat Cheung Dr Jamie Soul et al.	Increased hippocampal excitability in miR-324-null mice	2021
Dr Edward Fielder Dr Clare Tweedy Dr Caroline Wilson Professor Fiona Oakley Dr Fiona LeBeau et al.	Anti-inflammatory treatment rescues memory deficits during aging in nfkb1−/− mice	2020
Dr Myrto Stylianou Dr Boubker Zaaimi Professor Alan Thomas Professor John-Paul Taylor Dr Fiona LeBeau et al.	Early Disruption of Cortical Sleep-Related Oscillations in a Mouse Model of Dementia With Lewy Bodies (DLB) Expressing Human Mutant (A30P) Alpha-Synuclein	2020
Sabine Gretenkord Dr Bas Olthof Myrto Stylianou Professor Adrian Rees Dr Sasha Gartside et al.	Electrical stimulation of the ventral tegmental area (VTA) evokes sleep-like state transitions under urethane anaesthesia in the rat medial prefrontal cortex (mPFC) via dopamine D₁-like receptors	2020
Dr Zhe Kang Law Carein Todd Ramtin Mehraram Julia Schumacher Professor Mark Baker et al.	The role of EEG in the diagnosis, prognosis and clinical correlations of Dementia with Lewy Bodies—a systematic review	2020
Dr Fiona LeBeau Professor Ian McKeith Professor John-Paul Taylor	What electrophysiology tells us about Alzheimer's disease: a window into the synchronization and connectivity of brain neurons	2020
Dr Paul Keane Dr Peter Hanson Lina Patterson Professor Peter Blain Philippa Hepplewhite et al.	Trichloroethylene and its metabolite TaClo lead to degeneration of substantia nigra dopaminergic neurones: Effects in wild type and human A30P mutant α-synuclein mice	2019
Emma Robson Clare Tweedy Dr NELSON Manzanza Professor John-Paul Taylor Fiona Randall et al.	Impaired Fast Network Oscillations and Mitochondrial Dysfunction in a Mouse Model of Alpha-synucleinopathy (A30P)	2018
Myrto Stylianou Dr Nik Murphy Dr Luis Peraza Rodriguez Dr Sara Graziadio Dr Ruth Cromarty et al.	Quantitative electroencephalography as a marker of cognitive fluctuations in dementia with Lewy bodies and aid to differential diagnosis	2018
Sabine Gretenkord Professor Adrian Rees Professor Miles Whittington Dr Sasha Gartside Dr Fiona LeBeau et al.	Dorsal vs. ventral differences in fast Up-state-associated oscillations in the medial prefrontal cortex of the urethane-anesthetized rat	2017
Natalie Adams Professor Miles Whittington Dr Fiona LeBeau	Hetereogeneity in Neuronal Intrinsic Properties: A Possible Mechanism for Hub-Like Properties of the Rat Anterior Cingulate Cortex during Network Activity	2017
Professor John-Paul Taylor Daniel Collerton Dr Fiona LeBeau Emeritus Professor Elaine Perry	Cholinergic pathology in dementia with Lewy bodies	2016
Vasileios Glykos Professor Miles Whittington Dr Fiona LeBeau	Subregional differences in the generation of fast network oscillations in the rat medial prefrontal cortex (mPFC) in vitro	2015
Dr Claire Gillougley Dr Georgia Rentesi Dr Fiona LeBeau Mark Cunningham	Divergent actions of a Kv3 positive modulator on gamma frequency oscillations in the mammalian neocortex in vitro	2014
Vasileios Glykos Dr Fiona LeBeau	Bidirectional modulation of hippocampal gamma (20–80 Hz) frequency activity in vitro via alpha(α)- and beta(β)-adrenergic receptors (AR)	2013
Dr Fiona LeBeau	Cortical network oscillations in Alzheimer's disease: insights from rodent models	2013
Dr Fiona LeBeau	Minimal size of cell assemblies coordinated by gamma oscillations	2012
Professor Miles Whittington Professor Mark Cunningham Dr Fiona LeBeau Dr Claudia Racca	Multiple origins of the cortical gamma rhythm	2011
Mary Johnson Dr Fiona LeBeau Emeritus Professor Elaine Perry	Partial loss of parvalbumin-containing hippocampal interneurons in dementia with Lewy bodies	2011
Dr Anita Roopun Dr Fiona LeBeau Professor Mark Cunningham Professor Miles Whittington	Cholinergic neuromodulation controls directed temporal communication in neocortex in vitro	2010
Dr Steven Middleton Dr Fiona LeBeau Dr Anita Roopun Professor Miles Whittington Professor Mark Cunningham et al.	NMDA receptor-dependent switching between different gamma rhythm-generating microcircuits in entorhinal cortex	2008
Dr David Cox Dr Claudia Racca Dr Fiona LeBeau	β-adrenergic receptors are differentially expressed in distinct interneuron subtypes in the rat hippocampus	2008
Dr Steven Middleton Dr Claudia Racca Dr Helen Garner Dr Fiona LeBeau Professor Miles Whittington et al.	Beta rhythms (15-20 Hz) generated by nonreciprocal communication in hippocampus	2007
Dr Claudia Racca Professor Mark Cunningham Professor Miles Whittington Dr Fiona LeBeau	Impairment of hippocampal gamma (γ)-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP)	2007
Professor Mark Cunningham Dr Steven Middleton Dr Fiona LeBeau Professor Miles Whittington	Recruitment of Parvalbumin-Positive Interneurons Determines Hippocampal Function and Associated Behavior	2007
Dr Anita Roopun Dr Steven Middleton Professor Mark Cunningham Dr Fiona LeBeau Professor Miles Whittington et al.	A beta2-frequency (20-30 Hz) oscillation in nonsynaptic networks of somatosensory cortex	2006
Professor Mark Cunningham Judith Hunt Dr Steven Middleton Dr Fiona LeBeau Professor Miles Whittington et al.	Region-specific reduction in entorhinal gamma oscillations and parvalbumin-immunoreactive neurons in animal models of psychiatric illness	2006
Dr Claudia Racca Professor Mark Cunningham Judith Hunt Dr Steven Middleton Dr Fiona LeBeau et al.	Region-specific reduction in entorhinal gamma oscillations and parvalbumin-immunoreactive neurons in animal models of psychiatric illness	2006
Dr Fiona LeBeau	Microcircuits in action - From CPGs to neocortex	2005
Dr Fiona LeBeau Professor Miles Whittington	Oscillatory activity within rat substantia gelatinosa in vitro: a role for chemical and electrical neurotransmission	2005
Dr Fiona LeBeau Professor Mark Cunningham Professor Miles Whittington	Persistent gamma oscillations in superficial layers of rat auditory neocortex: experiment and model	2005
Professor Mark Cunningham Dr Fiona LeBeau Dr Anita Roopun Professor Miles Whittington	Single-Column Thalamocortical Network Model Exhibiting Gamma Oscillations, Sleep Spindles, and Epileptogenic Bursts	2005
Dr Fiona LeBeau	Synaptic pathways in neural microcircuits	2005
Dr Fiona LeBeau Professor Miles Whittington	Transient Depression of Excitatory Synapses on Interneurons Contributes to Epileptiform Bursts During Gamma Oscillations in the Mouse Hippocampal Slice	2005
Dr Fiona LeBeau	Tuning the network: Modulation of neuronal microcircuits in the spinal cord and hippocampus	2005
Professor Mark Cunningham Professor Miles Whittington Dr Anita Roopun Dr Fiona LeBeau	A role for fast rhythmic bursting neurons in cortical gamma oscillations in vitro	2004
Dr Fiona LeBeau Professor Miles Whittington	Cellular mechanisms of neuronal population oscillations in the hippocampus in vitro	2004
Dr Fiona LeBeau Professor Miles Whittington	Contrasting roles of axonal (pyramidal cell) and dendritic (interneuron) electrical coupling in the generation of neuronal network oscillations	2003
Professor Mark Cunningham Dr Fiona LeBeau Professor Miles Whittington	GABA-enhanced collective behavior in neuronal axons underlies persistent gamma-frequency oscillations	2003
Professor Miles Whittington Dr Fiona LeBeau	Sharp Wave-Like Activity in the Hippocampus In Vitro in Mice Lacking the Gap Junction Protein Connexin 36	2003
Dr Fiona LeBeau Professor Miles Whittington	The role of electrical signalling via gap junctions in the generation of fast network oscillations	2003
Dr Fiona LeBeau Professor Miles Whittington	A model of atropine-resistant theta oscillations in rat hippocampal area CA1	2002
Dr Fiona LeBeau Professor Miles Whittington	Fast network oscillations in the rat dentate gyrus in vitro	2002
Dr Fiona LeBeau Professor Miles Whittington	Fast network oscillations induced by potassium transients in the rat hippocampus in vitro	2002
Dr Fiona LeBeau Professor Miles Whittington	Fast network oscillations induced by potassium transients in the rat hippocampus in vitro	2002
Professor Miles Whittington Dr Fiona LeBeau	A possible role for gap junctions in generation of very fast EEG oscillations preceding the onset of, and perhaps initiating, seizures	2001
Professor Miles Whittington Dr Fiona LeBeau	Differential expression of synaptic and non-synaptic mechanisms underlying stimulus-induced gamma oscillations in vitro	2001
Dr Fiona LeBeau Professor Miles Whittington	Gap junctions between interneuron dendrites can enhance synchrony of gamma oscillations in distributed networks	2001
Dr Fiona LeBeau Professor Miles Whittington	Impaired Electrical Signaling Disrupts Gamma Frequency Oscillations in Connexin 36-Deficient Mice	2001
Dr Fiona LeBeau Professor Adrian Rees	Iontophoresis in vivo demonstrates a key role for GABAA and glycinergic inhibition in shaping frequency response areas in the inferior colliculus of guinea pig	2001
Dr Fiona LeBeau Professor Adrian Rees	Iontophoretic studies in the inferior colliculus in vivo demonstrate a key role for GABA and glycine receptor mediated inhibition in shaping frequency response areas	2001
Dr Fiona LeBeau	Physiology of the GABA and Glycine system	2001
Dr Fiona LeBeau Professor Miles Whittington	A model of gamma-frequency network oscillations induced in the rat CA3 region by carbachol in vitro	2000